Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976390 | 1.00 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL4818612 | 1.00 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL14596578 | 0.95 | KMT2A (0.37) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL4821470 | 0.91 | ALDH1A1 (0.33) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL14582398 | 0.91 | ALDH1A1 (0.33) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL23925419 | 0.91 | ALDH1A1 (0.33) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL23925421 | 0.91 | ALDH1A1 (0.33) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL977522 | 0.91 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3117730 | 0.91 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL80486 | 0.91 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | claimed |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-01 | — | — | US | claimed |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | claimed |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | claimed |
| US-20110152097-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | claimed |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | claimed |
| US-20100190645-A1 | SYNERGISTIC FUNGICIDAL ACTIVE COMPOUND COMBINATIONS COMPRISING FORMONONETIN | PLANT HEALTH CARE, INC. | 2010-07-29 | — | — | US | claimed |
| EP-2132989-A2 | Agent combinations | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | claimed |
| US-20090280981-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-11-12 | — | — | US | claimed |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-15 | — | — | US | claimed |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| EP-4653442-A1 | POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153202-A1 | POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS | 中国科学院上海有机化学研究所 | 2024-07-25 | — | — | WO | disclosed |
| EP-2903436-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | UNIV PENNSYLVANIA (US) | 2019-07-17 | — | — | EP | disclosed |
| EP-2903436-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | UNIV PENNSYLVANIA (US) | 2019-07-17 | — | — | EP | disclosed |
| WO-2005056560-A1 | PROCESS FOR THE PREPARATION OF TUBULIN INHIBITORS | WYETH (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20050124635-A1 | Process for the preparation of tubulin inhibitors | WYETH (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050090508-A1 | 6-[(Substituted)phenyl]triazolopyrimidines as anticancer agents | WYETH HOLDINGS CORPORATION (US) | 2005-04-28 | — | — | US | disclosed |
| WO-2005030775-A1 | 6-[(SUBSTITUTED)PHENYL]TRIAZOLOPYRIMIDINES AS ANTICANCER AGENTS | WYETH HOLDINGS CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20040176398-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152097-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | MAPK1 3326/4885KMT2A 263/4885MEN1 2774/4885 |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPK1 3681/4885KMT2A 1733/4885MEN1 2134/4885 |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | CYP51A1, CYP1A2, CYP3A7 | MAPK1 4210/4885KMT2A 1555/4885MEN1 1718/4885 |
| US-20140213557-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | MAPK1 3326/4885KMT2A 263/4885MEN1 2774/4885 |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | NAT1, ACAT1, CAT | MAPK1 2868/4885KMT2A 1304/4885MEN1 2107/4885 |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | MAPK1 4014/4885KMT2A 2104/4885MEN1 1780/4885 |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | MAPK1 4014/4885KMT2A 2104/4885MEN1 1780/4885 |
| US-20050124635-A1 | Process for the preparation of tubulin inhibitors | TUBB3, TUBA3C, TUBAL3 | MAPK1 638/4885KMT2A 2811/4885MEN1 2521/4885 |
| US-20040176398-A1 | Triazolopyrimidines | Q6ZSR9, UMPS, UPP1 | MAPK1 832/4885KMT2A 1946/4885MEN1 1976/4885 |
| US-20100190645-A1 | SYNERGISTIC FUNGICIDAL ACTIVE COMPOUND COMBINATIONS COMPRISING FORMONONETIN | CYP51A1, ERG28, CYP3A7 | MAPK1 2040/4885KMT2A 3587/4885MEN1 196/4885 |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | CYP51A1, CYP1A2, CYP4X1 | MAPK1 4014/4885KMT2A 2104/4885MEN1 1780/4885 |
| US-20050090508-A1 | 6-[(Substituted)phenyl]triazolopyrimidines as anticancer agents | ABCC1, ABCB1, TUBB6 | MAPK1 1575/4885KMT2A 3055/4885MEN1 4039/4885 |
| US-20090280981-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | CYP51A1, ERG28, CYP4X1 | MAPK1 3283/4885KMT2A 2897/4885MEN1 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.