SCHEMBL3437804

SCHEMBL3437804

OBOc1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
ALDH1A1 P00352 6/20 0.41
POLB P06746 4/20 0.41
PABPC1 P11940 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
XBP1 P17861 1/20 0.41
NFKB1 P19838 1/20 0.41
HTT P42858 1/20 0.41
SMARCA2 P51531 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
TSHR P16473 3/20 0.40
HSD17B10 Q99714 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483938 0.85 CRHBP (0.48) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL12586093 0.82 KDM4E (0.35) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL3437807 0.82 ALDH1A1 (0.39) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL3437806 0.79 MAPT (0.36) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL17522038 0.76 CRHBP (0.41) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL17577294 0.76 CYP2D6 (0.46) ALDH1A1MAPTKDM4EKMT2AHSD17B10
SCHEMBL16201008 0.75 PRMT1 (0.64) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL9466026 0.74 CRHBP (0.46) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL1208501 0.74 CRHBP (0.46) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL10197719 0.74 CRHBP (0.39) CRHBPCRHR2KEAP1NFE2L2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-11-02 US disclosed
US-20160218299-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-28 US disclosed
US-20160043327-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-02-11 US disclosed
US-20150364692-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-12-17 US disclosed
US-8822043-B2 Organic compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2014-09-02 US disclosed
US-20120091450-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160218299-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EFNA1, L1CAM, LEF1 CRHBP 4876/4885CRHR2 4675/4885KEAP1 2652/4885
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, PER2 CRHBP 4598/4885CRHR2 3515/4885KEAP1 1673/4885
US-20120091450-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE TRPA1, AFF4, TYR CRHBP 4506/4885CRHR2 4271/4885KEAP1 1991/4885
US-20150364692-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LEF1, EZH1, EPCAM CRHBP 4095/4885CRHR2 4173/4885KEAP1 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.