Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417754 | 1.00 | NOTUM (0.43) | NOTUMALDH1A1ACP1KIF11TAS2R14 | |
| SCHEMBL18002328 | 0.89 | ALDH1A1 (0.37) | NOTUMALDH1A1ACP1CES2RPS6KA3 | |
| SCHEMBL6856533 | 0.84 | CES2 (0.41) | ALDH1A1KIF11CES2RPS6KA3JAK3 | |
| SCHEMBL66819 | 0.84 | CES2 (0.46) | ALDH1A1KIF11CES2RPS6KA3JAK3 | |
| SCHEMBL15459002 | 0.81 | ALDH1A1 (0.37) | NOTUMALDH1A1KIF11 | |
| SCHEMBL15458957 | 0.81 | ALDH1A1 (0.37) | NOTUMALDH1A1KIF11 | |
| SCHEMBL1542624 | 0.79 | ALDH1A1 (0.42) | ALDH1A1POLB | |
| SCHEMBL30814317 | 0.79 | ALDH1A1 (0.42) | ALDH1A1POLB | |
| SCHEMBL1662267 | 0.79 | NOTUM (0.40) | NOTUMACP1TAS2R14CES2RPS6KA3 | |
| SCHEMBL16957678 | 0.79 | NOTUM (0.43) | NOTUMACP1TAS2R14CES2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092063-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | JAZZ PHARMACEUTICALS IRELAND LTD (IE) | 2026-04-02 | — | — | US | disclosed |
| US-12527325-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-20 | — | — | US | disclosed |
| EP-4655296-A1 | CBL-B INHIBITORS | Aurigene Oncology Limited (IN) | 2025-12-03 | — | — | EP | disclosed |
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |
| EP-3947358-B1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| EP-4570313-A2 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-12304912-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2025-05-20 | — | — | US | disclosed |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-22 | — | — | US | disclosed |
| US-20250122226-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2025-04-17 | — | — | US | disclosed |
| US-12258340-B2 | Pyrazole MAGL inhibitors | H. LUNDBECK A/S (DK) | 2025-03-25 | — | — | US | disclosed |
| US-20070225365-A1 | Cetp Inhibitors | MERCK & CO., INC. (US) | 2007-09-27 | — | — | US | disclosed |
| CN-1942428-A | CETP inhibitors | MERCK & CO INC (US) | 2007-04-04 | — | — | CN | disclosed |
| EP-1737811-A1 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| JP-2006045095-A | 3-FORMYL-5-TRIFLUOROMETHYLBENZONITRILE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | CENTRAL GLASS CO LTD | 2006-02-16 | — | — | JP | disclosed |
| CN-1708493-A | Selected CGRP antagonists, method for production and use thereof as medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-14 | — | — | CN | disclosed |
| WO-2005100298-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| JP-2005272324-A | 3-FORMYL-5-TRIFLUOROMETHYLBENZONITRILE DERIVATIVE AND ITS MANUFACTURING METHOD | CENTRAL GLASS CO LTD | 2005-10-06 | — | — | JP | disclosed |
| WO-2005090289-A1 | 3-FORMYL-5-TRIFLUOROMETHYLBENZONITRILE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2005-09-29 | — | — | WO | disclosed |
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527325-B2 | Pesticidally active diazine-amide compounds | DDT, CHRM1, C3AR1 | NOTUM 302/4885ALDH1A1 1101/4885ACP1 954/4885 |
| US-20070225365-A1 | Cetp Inhibitors | CETP, APOB, NPC1 | NOTUM 173/4885ALDH1A1 2315/4885ACP1 1786/4885 |
| US-12304912-B2 | Fused bicyclic RAF inhibitors and methods for use thereof | BRAF, RAF1, NRAS | NOTUM 3311/4885ALDH1A1 2065/4885ACP1 912/4885 |
| US-12258340-B2 | Pyrazole MAGL inhibitors | MGLL, PNLIP, LPL | NOTUM 94/4885ALDH1A1 2260/4885ACP1 602/4885 |
| US-20250122226-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | NOTUM 2218/4885ALDH1A1 1240/4885ACP1 326/4885 |
| US-20260092063-A1 | FUSED BICYCLIC RAF INHIBITORS AND METHODS FOR USE THEREOF | BRAF, NRAS, RAF1 | NOTUM 3378/4885ALDH1A1 2381/4885ACP1 1632/4885 |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | DDT, ACHE, NIT2 | NOTUM 236/4885ALDH1A1 787/4885ACP1 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.