Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165334 | 0.81 | MEN1 (0.57) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL27757412 | 0.80 | GOT1 (0.44) | LMNAMAPTDHFRCYP3A4 | |
| SCHEMBL8467926 | 0.78 | HDAC4 (0.46) | MEN1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL14802112 | 0.77 | BCHE (0.47) | MEN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27862933 | 0.77 | GABRG2 (0.48) | MEN1ALDH1A1MAP4K4KDM4EMAPT | |
| SCHEMBL27587153 | 0.77 | GABRG2 (0.53) | MEN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL913810 | 0.77 | NOTUM (0.47) | MAPTNPC1TSHRRAB9ACYP19A1 | |
| SCHEMBL121970 | 0.74 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29959678 | 0.74 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1018949 | 0.74 | ASIC3 (0.55) | MEN1PSIP1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058312-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | GAIN THERAPEUTICS SA (CH) | 2023-02-23 | — | — | US | disclosed |
| US-20230058312-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | GAIN THERAPEUTICS SA (CH) | 2023-02-23 | — | — | US | disclosed |
| CN-112695402-B | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2022-12-20 | — | — | CN | disclosed |
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| EP-4065546-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | Gain Therapeutics SA (CH) | 2022-10-05 | — | — | EP | disclosed |
| CN-110942918-B | Stacked capacitor, manufacturing method thereof and silver colloid layer | 钰冠科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112500568-B | Polyimide film and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-08-17 | — | — | CN | disclosed |
| WO-2021105906-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | GAIN THERAPEUTICS SA (CH) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021105906-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | GAIN THERAPEUTICS SA (CH) | 2021-06-03 | — | — | WO | disclosed |
| CN-112695402-A | Polyimide fiber and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-04-23 | — | — | CN | disclosed |
| US-7732445-B2 | Myosin light chain kinase inhibitor compounds, compostions and related methods of use | NORTHWESTERN UNIVERSITY (US) | 2010-06-08 | — | — | US | disclosed |
| WO-2008011176-A9 | MYOSIN LIGHT CHAIN KINASE INHIBITOR COMPOUNDS, COMPOSITIONS AND RELATED METHODS OF USE | UNIV NORTHWESTERN (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008011176-A2 | MYOSIN LIGHT CHAIN KINASE INHIBITOR COMPOUNDS, COMPOSITIONS AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20080021035-A1 | Myosin light chain kinase inhibitor compounds, compostions and related methods of use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
| CN-1198803-C | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | FIRST SUNTORY PHARMACEUTICAL L (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-20040266774-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6770667-B1 | N-((IMIDAZOLYL)-PHENYL)-FLUORENE-1-CARBOXAMIDE DERIVATIVES; 5-HYDROXYTRYPTAMINE (5-HT) ANTAGONISTS; PSYCHOLOGICAL, NERVOUS SYSTEM, EATING, BRAIN AND SLEEP DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| EP-1216240-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| CN-1349506-A | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | SUNTORY LTD (JP) | 2002-05-15 | — | — | CN | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230058312-A1 | ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE | GBA1, GALC, MAN2B1 | MEN1 4325/4885PSIP1 4712/4885AXL 3625/4885 |
| US-20080021035-A1 | Myosin light chain kinase inhibitor compounds, compostions and related methods of use | MYLK, MYLK3, MYLK2 | MEN1 3051/4885PSIP1 3820/4885AXL 652/4885 |
| US-20040266774-A1 | Amide compounds | TPH1, HTR1A, HTR5A | MEN1 1936/4885PSIP1 537/4885AXL 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.