Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.32 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895263 | 0.75 | KDM4E (0.43) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6894924 | 0.75 | KDM4E (0.43) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6895745 | 0.74 | LMNA (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6895959 | 0.73 | ADRA2C (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6894568 | 0.73 | CYP3A4 (0.44) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6893034 | 0.72 | HPGD (0.53) | KDM4EALDH1A1CYP3A4HPGDCYP2C19 | |
| SCHEMBL6889436 | 0.71 | SIGMAR1 (0.49) | LMNAADRA2AHIF1AALDH1A1AOC3 | |
| SCHEMBL6895074 | 0.70 | HPGD (0.44) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7360281 | 0.70 | KDM4E (0.40) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL4691512 | 0.70 | KMT2A (0.52) | LMNAADRA2AADRA2CHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |