Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412576 | 1.00 | ALDH3A1 (0.54) | ALDH3A1POLBLMNAL3MBTL1NOD1 | |
| SCHEMBL3470885 | 0.88 | ALDH3A1 (0.56) | ALDH3A1POLBLMNANOD1PKM | |
| SCHEMBL3470253 | 0.88 | ALOX5 (0.65) | ALDH3A1LMNAL3MBTL1NOD1PKM | |
| SCHEMBL32670676 | 0.83 | POLB (0.49) | ALDH3A1POLBLMNAL3MBTL1PKM | |
| SCHEMBL3472693 | 0.82 | ALDH3A1 (0.62) | ALDH3A1LMNAL3MBTL1NOD1TSHR | |
| SCHEMBL3471021 | 0.81 | ALDH3A1 (0.45) | ALDH3A1LMNANOD1PKMALOX5 | |
| SCHEMBL3470648 | 0.81 | ALOX5 (0.75) | ALDH3A1POLBLMNAL3MBTL1NOD1 | |
| SCHEMBL7565277 | 0.79 | ALDH1A1 (0.60) | POLBLMNAL3MBTL1ALOX5TSHR | |
| SCHEMBL13032907 | 0.79 | ALDH3A1 (0.60) | ALDH3A1LMNANOD1PKMALOX5 | |
| SCHEMBL13077259 | 0.75 | ALDH3A1 (0.57) | ALDH3A1POLBLMNANOD1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12599665-B2 | Gene fusions for control of genetically modified cells | A2 BIOTHERAPEUTICS, INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-20230330227-A1 | GENE FUSIONS FOR CONTROL OF GENETICALLY MODIFIED CELLS | A2 BIOTHERAPEUTICS, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230270699-A1 | METHOD FOR MODULATING METABOLISM | Sanford Burnham Prebys Medical Discovery Institute | 2023-08-31 | — | — | US | disclosed |
| US-11642323-B2 | Method for modulating metabolism | BRIGHTSEED, INC. (US) | 2023-05-09 | — | — | US | disclosed |
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | BUMHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | BUMHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-16 | — | — | US | disclosed |
| WO-2010127246-A2 | HNF4 MODULATORS AND METHODS OF USE | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11642323-B2 | Method for modulating metabolism | GOT2, GYS2, PC | ALDH3A1 396/4885POLB 2946/4885LMNA 3934/4885 |
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | HNF4A, NCOA4, NR4A3 | ALDH3A1 865/4885POLB 428/4885LMNA 1739/4885 |
| US-20230270699-A1 | METHOD FOR MODULATING METABOLISM | GOT2, GYS2, PC | ALDH3A1 396/4885POLB 2946/4885LMNA 3934/4885 |
| US-20230330227-A1 | GENE FUSIONS FOR CONTROL OF GENETICALLY MODIFIED CELLS | BAX, TIAL1, CCAR2 | ALDH3A1 4034/4885POLB 4584/4885LMNA 2051/4885 |
| US-12599665-B2 | Gene fusions for control of genetically modified cells | BID, ESR1, BCLAF1 | ALDH3A1 4612/4885POLB 3545/4885LMNA 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.