Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970472 | 0.96 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL23075729 | 0.90 | OPRM1 (0.40) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10350856 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL9136425 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL690816 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL4022359 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL17253503 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL19219115 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL11673316 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH | |
| SCHEMBL3039218 | 0.87 | DNM1 (0.48) | THRBEPHX2SPHK1DNM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655824-B2 | Use of diphenylmethane derivatives as tyrosinase inhibitors | SYMRISE AG (DE) | 2017-05-23 | — | — | US | disclosed |
| US-9526687-B2 | Polymers based on sulfonic acids, amides and special cross-linking agents | CLARIANT INTERNATIONAL LTD. (CH) | 2016-12-27 | — | — | US | disclosed |
| US-20140086854-A1 | Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-03-27 | — | — | US | disclosed |
| US-8409552-B2 | Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds | SYMRISE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | SYMRISE AG (DE) | 2012-12-13 | — | — | US | disclosed |
| US-8241681-B2 | Synergistic mixtures of bisabolol and ginger extract | SYMRISE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-8203016-B2 | Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents | SYMRISE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20100216892-A1 | Use of synergistically active 1,2-alkanediol mixtures as skin moisture-regulating compositions | SYMRISE GMBH & CO. KG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20090220625-A1 | SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT | SYMRISE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| US-7582681-B2 | Synergistic mixtures of 1,2-alkane diols | SYMRISE GMBH & CO. KG (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1937366-A1 | SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT | Symrise GmbH & Co. KG (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1835843-A1 | USE OF SYNERGISTICALLY ACTIVE 1,2-ALKANEDIOL MIXTURES AS SKIN MOISTURE-REGULATING COMPOSITIONS | Symrise GmbH & Co. KG (DE) | 2007-09-26 | — | — | EP | disclosed |
| US-20070098655-A1 | Use of diphenylmethane derivatives as tyrosinase inhibitors | SYMRISE AG (DE) | 2007-05-03 | — | — | US | disclosed |
| WO-2007042472-A1 | SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT | SYMRISE GMBH & CO. KG (DE) | 2007-04-19 | — | — | WO | disclosed |
| WO-2006069953-A1 | USE OF SYNERGISTICALLY ACTIVE 1, 2-ALKANEDIOL MIXTURES AS SKIN MOISTURE-REGULATING COMPOSITIONS | SYMRISE GMBH & CO. KG (DE) | 2006-07-06 | — | — | WO | disclosed |
| US-20060089413-A1 | Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents | SYMRISE GMBH & CO. KG (DE) | 2006-04-27 | — | — | US | disclosed |
| US-20050222276-A1 | Synergistic mixtures of 1,2-alkane diols | SYMRISE AG (DE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222276-A1 | Synergistic mixtures of 1,2-alkane diols | BAK1, ERG28, ADH1A | HTT 4778/4885MEN1 1326/4885THRB 2742/4885 |
| US-20060089413-A1 | Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents | HRH1, CMA1, HRH2 | HTT 2533/4885MEN1 1771/4885THRB 4403/4885 |
| US-20140086854-A1 | Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents | ACMSD, SRM, TAS1R1 | HTT 884/4885MEN1 2109/4885THRB 4471/4885 |
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | CMA1, TPSAB1, HRH1 | HTT 2046/4885MEN1 1612/4885THRB 4482/4885 |
| US-20070098655-A1 | Use of diphenylmethane derivatives as tyrosinase inhibitors | TYR, DPM1, DDT | HTT 2307/4885MEN1 2900/4885THRB 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.