Sugi Predict

Sugi Predict / Compounds / SCHEMBL35222

SCHEMBL35222

SCHEMBL35222

CS(=O)(=O)c1cccc(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 2/20 0.54
▸ HSD17B1 P14061 3/20 0.50
▸ HSD17B2 P37059 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.48
▸ CA2 P00918 2/20 0.48
▸ HSD17B10 Q99714 2/20 0.48
▸ CA12 O43570 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CA5A P35218 1/20 0.48
▸ CA9 Q16790 1/20 0.48
▸ CA14 Q9ULX7 1/20 0.48
▸ CA5B Q9Y2D0 1/20 0.48
▸ PTGS2 P35354 1/20 0.46
▸ SCD O00767 1/20 0.46
▸ ACHE P22303 1/20 0.44
▸ MMP2 P08253 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ SMO Q99835 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577268 1.00 ENPP2 (0.54) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL18445871 0.84 HSD17B1 (0.49) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL10051059 0.83 CA1 (0.55) ENPP2ALDH1A1CA2HSD17B10SMN1; SMN2
SCHEMBL31146723 0.81 CA2 (0.61) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL69135 0.81 CA2 (0.61) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL10340796 0.81 CA2 (0.61) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL31366862 0.79 ALDH1A1 (0.59) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL30817410 0.79 ALDH1A1 (0.59) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL487038 0.79 ALDH1A1 (0.59) ENPP2HSD17B1HSD17B2ALDH1A1CA2
SCHEMBL10587183 0.79 CA2 (0.59) ENPP2HSD17B1HSD17B2ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115798935-A Electrolytic capacitor 松下知识产权经营株式会社 2023-03-14 — — CN claimed
CN-111383845-B Electrolytic capacitor 松下知识产权经营株式会社 2023-01-24 — — CN claimed
CN-111383845-A Electrolytic capacitor 松下知识产权经营株式会社 2020-07-07 — — CN claimed
US-12570645-B2 Uses of p53 x-ray co-crystal structures PMV PHARMACEUTICALS, INC. (US) 2026-03-10 — — US disclosed
US-20260027097-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS INC (US) 2026-01-29 — — US disclosed
EP-4642772-A1 NLRP3 INFLAMMASOME INHIBITORS Astrazeneca AB (SE) 2025-11-05 — — EP disclosed
US-20250319063-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV PHARMACEUTICALS, INC. 2025-10-16 — — US disclosed
US-12428406-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2025-09-30 — — US disclosed
US-12419880-B2 Companion diagnostic tool for mutant p53 reactivating compounds PMV PHARMACEUTICALS, INC. (US) 2025-09-23 — — US disclosed
US-12421193-B2 GPR52 modulators and methods of use NEUROCRINE BIOSCIENCES, INC. (US) 2025-09-23 — — US disclosed
US-20250243168-A1 ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME THE WISTAR INST (US) 2025-07-31 — — US disclosed
EP-0053011-B1 NEW HERBICIDAL NICOTINAMIDE DERIVATIVES MAY & BAKER LIMITED (GB) 1985-04-03 — — EP disclosed
EP-0053011-A1 New herbicidal nicotinamide derivatives MAY & BAKER LIMITED (GB) 1982-06-02 — — EP disclosed
US-4213969-A Phosphonous acid derivatives, processes for their preparation and their use in combatting microorganisms CIBA-GEIGY CORPORATION (US) 1980-07-22 — — US disclosed
EP-0002039-A1 Phosphonous acid derivatives, processes for their preparation and their use in combating microorganisms CIBA-GEIGY AG (CH) 1979-05-30 — — EP disclosed
US-4126629-A FERTILITY CONTROL MERCK & CO., INC. (US) 1978-11-21 — — US disclosed
US-4061643-A ANTIFERTILITY MERCK & CO., INC. (US) 1977-12-06 — — US disclosed
US-4055596-A PHARMACEUTICALS MERCK & CO., INC. (US) 1977-10-25 — — US disclosed
US-4020177-A CONTRACEPTIVES MERCK & CO., INC. (US) 1977-04-26 — — US disclosed
US-3991106-A FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY MERCK & CO., INC. (US) 1976-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428406-B2 Methods and compounds for restoring mutant p53 function TP53, TP53BP1, KRAS ENPP2 3096/4885HSD17B1 3017/4885HSD17B2 3279/4885
US-20250319063-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION TP53, TP53BP1, KRAS ENPP2 3094/4885HSD17B1 2857/4885HSD17B2 3149/4885
US-20260027097-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION TP53, TP53BP1, BRCA1 ENPP2 4385/4885HSD17B1 4401/4885HSD17B2 4442/4885
US-12570645-B2 Uses of p53 x-ray co-crystal structures TP53, TP53BP1, ERCC2 ENPP2 4455/4885HSD17B1 1326/4885HSD17B2 1978/4885
US-12419880-B2 Companion diagnostic tool for mutant p53 reactivating compounds TP53, TP53BP1, KRAS ENPP2 3715/4885HSD17B1 3832/4885HSD17B2 3798/4885
US-20250243168-A1 ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME ACSS2, ACACB, ACACA ENPP2 769/4885HSD17B1 1264/4885HSD17B2 1210/4885
US-12421193-B2 GPR52 modulators and methods of use GPR52, GPR68, GPR35 ENPP2 172/4885HSD17B1 1245/4885HSD17B2 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.