Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352322 | 1.00 | HSD17B10 (0.52) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL28901123 | 1.00 | HSD17B10 (0.52) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL28294751 | 0.98 | HSD17B10 (0.50) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL30057643 | 0.94 | HSD17B10 (0.47) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL13527786 | 0.88 | HSD17B10 (0.61) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL3306654 | 0.82 | MEN1 (0.49) | KMT2AMEN1CYP2C19CYP1A2ALOX5 | |
| Oxfenicine SCHEMBL122315 | 0.79 | HSD17B10 (0.55) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| Oxfenicine SCHEMBL652186 | 0.79 | HSD17B10 (0.55) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL2262988 | 0.79 | HSD17B10 (0.53) | HSD17B10KMT2ATDP1MEN1CYP2C9 | |
| SCHEMBL5329159 | 0.79 | HSD17B10 (0.53) | HSD17B10KMT2ATDP1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120005341-A | Acrylic plate with sound insulation function and preparation process thereof | 浙江伸美压克力股份有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-113161452-B | Perovskite thin film, perovskite LED device and preparation method thereof | 湖北大学 | 2023-03-24 | — | — | CN | claimed |
| CN-113161452-A | Perovskite thin film, perovskite LED device and preparation method thereof | 湖北大学 | 2021-07-23 | — | — | CN | claimed |
| US-12503452-B2 | Antimicrobial compounds and methods | CURZA GLOBAL, LLC (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4225304-B1 | SYNTHESIS OF EGFR MODULATORS | UNIV MICHIGAN REGENTS (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-120005341-A | Acrylic plate with sound insulation function and preparation process thereof | 浙江伸美压克力股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| US-20240018144-A1 | Synthesis of EGFR Modulators | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-01-18 | — | — | US | disclosed |
| US-20240018144-A1 | Synthesis of EGFR Modulators | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-01-18 | — | — | US | disclosed |
| US-20240018144-A1 | Synthesis of EGFR Modulators | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-01-18 | — | — | US | disclosed |
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| CN-116997551-A | Synthesis of EGFR modulators | 密歇根大学董事会 | 2023-11-03 | — | — | CN | disclosed |
| CN-101248046-A | Amide derivatives as kinase inhibitors | DEVGEN NV (BE) | 2008-08-20 | — | — | CN | disclosed |
| CN-101238127-A | Pyrimidine or triazine fused bicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS INC (US) | 2008-08-06 | — | — | CN | disclosed |
| US-20080161300-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| EP-1907362-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | Devgen NV (BE) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007096259-A1 | HYDANTOIN BASED KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-30 | — | — | WO | disclosed |
| US-20070197617-A1 | Substituted hydantoins | CHEN SHAOQING | 2007-08-23 | — | — | US | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| WO-2007006547-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |
| US-20060293345-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197617-A1 | Substituted hydantoins | HNMT, HRH3, BRAF | HSD17B10 1072/4885KMT2A 179/4885TDP1 554/4885 |
| US-20060293345-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, MMP3, MMP10 | HSD17B10 458/4885KMT2A 3364/4885TDP1 2102/4885 |
| US-20080161300-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | HSD17B10 501/4885KMT2A 3548/4885TDP1 2304/4885 |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | HSD17B10 501/4885KMT2A 3548/4885TDP1 2304/4885 |
| US-20240018144-A1 | Synthesis of EGFR Modulators | EGFR, ERBB2, ERBB4 | HSD17B10 3585/4885KMT2A 3424/4885TDP1 4743/4885 |
| US-12503452-B2 | Antimicrobial compounds and methods | MPO, NISCH, RPN2 | HSD17B10 3006/4885KMT2A 4067/4885TDP1 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.