SCHEMBL3527405

SCHEMBL3527405

COc1ccc(Cl)c(OC)c1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.76
KDM4E B2RXH2 1/20 0.76
HSD17B10 Q99714 1/20 0.76
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
TSHR P16473 1/20 0.53
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TAS1R3 Q7RTX0 6/20 0.45
TAS1R1 Q7RTX1 6/20 0.45
TAS1R2 Q8TE23 4/20 0.45
FABP4 P15090 1/20 0.43
CLCN2 P51788 1/20 0.43
TPMT P51580 2/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495000 1.00 ALDH1A1 (0.76) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL29539000 0.86 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL18336 0.86 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL1932787 0.86 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10CA12CA1
SCHEMBL14416606 0.85 ALDH1A1 (0.59) ALDH1A1KDM4EHSD17B10CA12CA1
SCHEMBL11165767 0.85 ALDH1A1 (0.76) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL1702321 0.85 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL1682195 0.85 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10CA12CA1
3,6 Dichloromethoxybenzoic Acid SCHEMBL2369132 0.85 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10CA12CA1
SCHEMBL3057430 0.85 ALDH1A1 (0.63) ALDH1A1KDM4EHSD17B10CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157284-A1 HIGH-LOAD SOLUTION CONCENTRATES OF DICAMBA BASF CORPORATION 2023-05-25 US claimed
US-20230148590-A1 Aqueous Formulations of Dicamba BASF CORPORATION 2023-05-18 US claimed
EP-4132274-A1 HIGH-LOAD SOLUTION CONCENTRATES OF DICAMBA BASF Corporation (US) 2023-02-15 EP claimed
EP-4125365-A1 AQUEOUS FORMULATIONS OF DICAMBA BASF Corporation (US) 2023-02-08 EP claimed
CN-115426880-A Aqueous formulations of dicamba 巴斯夫公司 2022-12-02 CN claimed
CN-115361868-A High-load solution concentrates of dicamba 巴斯夫公司 2022-11-18 CN claimed
WO-2021198458-A1 AQUEOUS FORMULATIONS OF DICAMBA BASF CORPORATION (US) 2021-10-07 WO claimed
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-17 US disclosed
WO-2024243289-A2 GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE THE CLEVELAND CLINIC FOUNDATION (US) 2024-11-28 WO disclosed
US-20240165131-A1 TREATING AND PREVENTING DISEASE WITH TMA AND TMAO LOWERING AGENTS THE CLEVELAND CLINIC FOUNDATION 2024-05-23 US disclosed
US-20240139120-A1 TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY THE CLEVELAND CLINIC FOUNDATION 2024-05-02 US disclosed
US-11911399-B2 Treating and preventing disease with TMA and TMAO lowering agents THE CLEVELAND CLINIC FOUNDATION (US) 2024-02-27 US disclosed
EP-4299064-A2 TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY THE CLEVELAND CLINIC FOUNDATION (US) 2024-01-03 EP disclosed
EP-1193261-A1 New thiadiazoles and their use as phosphodiesterase-7 inhibitors WARNER-LAMBERT COMPANY (US) 2002-04-03 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0810207-A1 Bis-ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-03 EP disclosed
EP-0004831-B1 2,6-DIALKOXYBENZAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND THESE COMPOUNDS FOR USE IN THE TREATMENT OF PSYCHOTIC DISORDES Astra Läkemedel Aktiebolag (SE) 1983-02-16 EP disclosed
US-4232037-A 2,6-Dialkoxybenzamides, intermediates, pharamaceutical compositions and methods for treatment of psychotic disorders ASTRA LAKEMEDEL AKTIEBOLAG (SE) 1980-11-04 US disclosed
EP-0004831-A2 2,6-Dialkoxybenzamides, process for their preparation, compositions and these compounds for use in the treatment of psychotic disordes Astra Läkemedel Aktiebolag (SE) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911399-B2 Treating and preventing disease with TMA and TMAO lowering agents MAOB, DAO, ESD ALDH1A1 239/4885KDM4E 1290/4885HSD17B10 402/4885
US-20240139120-A1 TREATING DISEASE AND PROMOTING WEIGHT LOSS BY INHIBITING THE TMA/FMO3/TMAO PATHWAY SLC5A2, SLC5A1, MAT1A ALDH1A1 1973/4885KDM4E 2023/4885HSD17B10 713/4885
US-20230148590-A1 Aqueous Formulations of Dicamba BOLA2; BOLA2B, CIP2A, AQP1 ALDH1A1 3828/4885KDM4E 3477/4885HSD17B10 1656/4885
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels BHMT, BHMT2, EHMT2 ALDH1A1 1296/4885KDM4E 270/4885HSD17B10 2588/4885
US-20230157284-A1 HIGH-LOAD SOLUTION CONCENTRATES OF DICAMBA PDHB, PDHA1, LDHB ALDH1A1 1726/4885KDM4E 1320/4885HSD17B10 178/4885
US-20240165131-A1 TREATING AND PREVENTING DISEASE WITH TMA AND TMAO LOWERING AGENTS MAOB, DAO, ESD ALDH1A1 239/4885KDM4E 1290/4885HSD17B10 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.