SCHEMBL353503

SCHEMBL353503

CCCCCCCCCCCCCCC(O)C(=O)OC(=O)C(O)CCCCCCCCCCCCCC

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.63
FFAR1 O14842 2/20 0.63
NAAA Q02083 1/20 0.52
ZDHHC7 Q9NXF8 1/20 0.50
FFAR4 Q5NUL3 1/20 0.47
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6037463 1.00 GPR84 (0.63) GPR84FFAR1NAAAZDHHC7FFAR4
SCHEMBL353158 1.00 GPR84 (0.63) GPR84FFAR1NAAAZDHHC7FFAR4
SCHEMBL353980 1.00 GPR84 (0.63) GPR84FFAR1NAAAZDHHC7FFAR4
SCHEMBL1123301 0.92 GPR84 (0.55) GPR84FFAR1NAAAZDHHC7MAPT
SCHEMBL127955 0.92 GPR84 (0.55) GPR84FFAR1NAAAZDHHC7MAPT
SCHEMBL1123651 0.92 GPR84 (0.55) GPR84FFAR1NAAAZDHHC7MAPT
SCHEMBL15011530 0.90 GPR84 (0.57) GPR84FFAR1NAAAZDHHC7FFAR4
SCHEMBL9722908 0.90 GPR84 (0.57) GPR84FFAR1NAAAZDHHC7FFAR4
SCHEMBL19695188 0.87 MAPT (0.54) GPR84FFAR1NAAAFFAR4MAPT
SCHEMBL9722954 0.87 GPR84 (0.53) GPR84FFAR1NAAAZDHHC7FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120093737-A1 LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS, INC. 2012-04-19 US disclosed
US-20120076842-A1 COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING SEDERMA (FR) 2012-03-29 US disclosed
EP-2419076-A2 COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES Sederma (FR) 2012-02-22 EP disclosed
US-20120028916-A1 COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES SEDERMA (FR) 2012-02-02 US disclosed
US-20120014887-A1 NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES SEDERMA (FR) 2012-01-19 US disclosed
EP-2382231-A2 NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES Sederma (FR) 2011-11-02 EP disclosed
EP-2382230-A2 KXK-PEPTIDE COMPOSITIONS FOR COSMETIC AND DERMO-PHARMACEUTIC USES Sederma (FR) 2011-11-02 EP disclosed
US-20110250276-A1 Cosmetic Composition Containing Acetylated Oligoglucuronans SEDERMA, S.A.S. (FR) 2011-10-13 US disclosed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP disclosed
EP-2046283-B1 COMPOSITION COMPRISING SARSASAPOGENIN SEDERMA SA (FR) 2011-03-16 EP disclosed
US-20110045036-A1 Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle SEDERMA (FR) 2011-02-24 US disclosed
US-20110033507-A1 Polypeptides KXK and Their Use SEDERMA (FR) 2011-02-10 US disclosed
US-20110002865-A1 MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL SEDERMA, S.A.S. (FR) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120014887-A1 NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES CUTA, PLOD3, MC1R GPR84 836/4885FFAR1 1453/4885NAAA 2354/4885
US-20110033507-A1 Polypeptides KXK and Their Use NPR3, NGLY1, NPR1 GPR84 627/4885FFAR1 1527/4885NAAA 1303/4885
US-20120076842-A1 COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING ARGLU1, CUTA, ARG1 GPR84 300/4885FFAR1 1033/4885NAAA 970/4885
US-20110045036-A1 Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle TYR, XPA, MC1R GPR84 2207/4885FFAR1 3605/4885NAAA 708/4885
US-20110002865-A1 MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL AQP1, CUTA, AQP3 GPR84 1922/4885FFAR1 2540/4885NAAA 2565/4885
US-20110250276-A1 Cosmetic Composition Containing Acetylated Oligoglucuronans GLA, OGA, CUTA GPR84 1356/4885FFAR1 2758/4885NAAA 984/4885
US-20120028916-A1 COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES DPM1, MC1R, SLTM GPR84 2434/4885FFAR1 2328/4885NAAA 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.