SCHEMBL35383

SCHEMBL35383

C=CN1C(=O)C1C(C)CCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 1/20 0.33
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20526212 0.83 MMP9 (0.30) MMP9
SCHEMBL2367994 0.80
SCHEMBL510489 0.79 MEN1 (0.31)
SCHEMBL27685291 0.71 MMP9 (0.31) MMP9
SCHEMBL1618688 0.70
SCHEMBL2367586 0.64
SCHEMBL632195 0.64
SCHEMBL2368023 0.64 SORT1 (0.33) FAAH
SCHEMBL868123 0.61
SCHEMBL24376349 0.60 PTPN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
EP-3759528-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20250347826-A1 METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-13 US claimed
US-20250340028-A1 CONTACT LENSES WITH SOFTER LENS SURFACES ALCON INC (CH) 2025-11-06 US claimed
US-20030162862-A1 Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing JOHNSON & JOHNSON VISION CARE, INC. 2003-08-28 US claimed
US-20030125498-A1 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. 2003-07-03 US claimed
WO-2003022322-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
WO-2003022321-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
CN-1283280-A Actively controllable multifocal lens NOVARTIS AG (CH) 2001-02-07 CN claimed
EP-1044389-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS Novartis AG (CH) 2000-10-18 EP claimed
US-5997140-A Actively controllable multifocal lens NOVARTIS AG (CH) 1999-12-07 US claimed
WO-1999034239-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS NOVARTIS AG (CH) 1999-07-08 WO claimed
US-4123408-A Hydrogel contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed
US-4123407-A Hydrophilic contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA MMP9 3923/4885FAAH 3238/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L MMP9 4616/4885FAAH 3553/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA MMP9 4041/4885FAAH 4264/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ MMP9 1813/4885FAAH 913/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA MMP9 4245/4885FAAH 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.