Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971993 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL3550116 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTCYP3A4ALOX15 | |
| SCHEMBL10694655 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL3551511 | 0.82 | KMT2A (0.60) | ALDH1A1TSHRKMT2ACYP3A4ALOX15 | |
| SCHEMBL398463 | 0.80 | HSD17B10 (0.60) | ALDH1A1TSHRKMT2AMAPTCYP3A4 | |
| SCHEMBL2243892 | 0.80 | GPR35 (0.56) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL4954263 | 0.80 | L3MBTL1 (0.63) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL16957420 | 0.80 | HTT (0.50) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL510143 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 | |
| SCHEMBL284069 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
| US-7820144-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820144-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2010-10-26 | — | — | US | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7501438-B2 | Pyridoimidazole derivatives | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-03-10 | — | — | US | disclosed |
| US-20080090871-A1 | CANNABIMIMETIC INDOLE DERIVATIVES | MAKRIYANNIS ALEXANDROS | 2008-04-17 | — | — | US | disclosed |
| US-20080090871-A1 | CANNABIMIMETIC INDOLE DERIVATIVES | MAKRIYANNIS ALEXANDROS | 2008-04-17 | — | — | US | disclosed |
| US-20080009491-A1 | 1-(3-naphthalen-1-yl-imidazo[1,5-a]pyridin-1-yl)-butan-1-one; chronic pain, an inflammatory disorder, rheumatoid arthritis, multiple sclerosis, osteoporosis and osteoarthritis; cannabinoid receptor ligands | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-01-10 | — | — | US | disclosed |
| WO-2008005908-A2 | PYRIDOIMIDAZOLE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-01-10 | — | — | WO | disclosed |
| US-20070243134-A1 | Receptor Selective Cannabimimetic Aminoalkylindoles | CONNECTICUT, UNIVERSITY OF | 2007-10-18 | — | — | US | disclosed |
| US-20070243134-A1 | Receptor Selective Cannabimimetic Aminoalkylindoles | CONNECTICUT, UNIVERSITY OF | 2007-10-18 | — | — | US | disclosed |
| US-7241799-B2 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241799-B2 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2007-07-10 | — | — | US | disclosed |
| US-7173027-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173027-B2 | Receptor selective cannabimimetic aminoalkylindoles | UNIVERSITY OF CONNECTICUT (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070243134-A1 | Receptor Selective Cannabimimetic Aminoalkylindoles | CNR2, CNR1, GPR18 | ALDH1A1 3295/4885TSHR 712/4885KMT2A 3752/4885 |
| US-20080009491-A1 | 1-(3-naphthalen-1-yl-imidazo[1,5-a]pyridin-1-yl)-butan-1-one; chronic pain, an inflammatory disorder, rheumatoid arthritis, multiple sclerosis, osteoporosis and osteoarthritis; cannabinoid receptor ligands | CNR1, CNR2, OPRK1 | ALDH1A1 3016/4885TSHR 1076/4885KMT2A 3100/4885 |
| US-20080090871-A1 | CANNABIMIMETIC INDOLE DERIVATIVES | CNR2, CNR1, GPR34 | ALDH1A1 3604/4885TSHR 1781/4885KMT2A 3354/4885 |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | ALDH1A1 544/4885TSHR 4030/4885KMT2A 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.