Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434344 | 0.90 | KDM4E (0.43) | GAAMEN1KMT2AL3MBTL1CHRNB2 | |
| SCHEMBL2432680 | 0.90 | KDM4E (0.43) | GAAMEN1KMT2AL3MBTL1CHRNB2 | |
| SCHEMBL4808129 | 0.84 | CHRNB2 (0.57) | GAAL3MBTL1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL28524412 | 0.82 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2429206 | 0.82 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL30213329 | 0.77 | GPR119 (0.45) | GAAMEN1KMT2AMAPTKCNH2 | |
| SCHEMBL21522595 | 0.76 | CHRNB2 (0.53) | L3MBTL1CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL2433695 | 0.75 | CHRNB2 (0.56) | MEN1KMT2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL7366249 | 0.75 | CHEK2 (0.58) | MAPTHPGDNPSR1 | |
| SCHEMBL3578221 | 0.73 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076202-A1 | METHOD FOR PRODUCING PYRROLIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20070149607-A1 | Method for producing pyrrolidine derivative | DAICHI PAHARMACEUTICAL CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1698621-A1 | METHOD FOR PRODUCING PYRROLIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076202-A1 | METHOD FOR PRODUCING PYRROLIDINE DERIVATIVE | ALDH18A1, PLAAT4, ACSL4 | GAA 588/4885MEN1 3920/4885KMT2A 647/4885 |
| US-20070149607-A1 | Method for producing pyrrolidine derivative | ALDH18A1, PLAAT4, ACSL4 | GAA 588/4885MEN1 3920/4885KMT2A 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.