SCHEMBL357322

SCHEMBL357322

Cc1cccccccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ACHE P22303 2/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
HPGDS O60760 1/20 0.33
DAO P14920 1/20 0.33
FBP1 P09467 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
RECQL P46063 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
PDPK1 O15530 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30418396 1.00 TSHR (0.40) TSHRACHELMNAALOX12HPGDS
Hydrochloric Acid SCHEMBL150092 0.97 TSHR (0.38) TSHRACHELMNAALOX12HPGDS
Water SCHEMBL17220159 0.97 TSHR (0.38) TSHRACHELMNAALOX12HPGDS
Water SCHEMBL1461353 0.97 TSHR (0.38) TSHRACHELMNAALOX12HPGDS
SCHEMBL29035078 0.97 TSHR (0.38) TSHRACHELMNAALOX12HPGDS
Hydrochloric Acid SCHEMBL30018178 0.97 TSHR (0.38) TSHRACHELMNAALOX12HPGDS
Hydrochloric Acid SCHEMBL28785708 0.95 TSHR (0.36) TSHRACHELMNAALOX12HPGDS
Hydrochloric Acid SCHEMBL30492120 0.95 TSHR (0.36) TSHRACHELMNAALOX12HPGDS
Benzene SCHEMBL1522440 0.91 DAO (0.40) TSHRACHELMNAALOX12HPGDS
SCHEMBL9413954 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115200-A1 Treatments Using Methylthioninium Salt, Liquid Mineral Blends, and/or Secondary Physiologically Active Compounds With Physiological Therapies BEST 365 LABS INC (US) 2026-04-30 US claimed
US-20260083747-A1 COMPOSITIONS AND METHODS FOR SUPPORTING MITOCHONDRIAL HEALTH LOPEZ DARREN (US) 2026-03-26 US claimed
US-20260048066-A1 TREATMENT OF NEURODEGENERATIVE DISORDERS UTILISING METHYLTHIONINIUM (MT)-CONTAINING COMPOUNDS WISTA LABORATORIES LTD (SG) 2026-02-19 US claimed
EP-4385512-B1 OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS TAURX THERAPEUTICS MAN LTD (GB) 2025-12-03 EP claimed
EP-4364801-B1 OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS TAURX THERAPEUTICS MAN LTD (GB) 2025-11-12 EP claimed
US-20250302843-A1 OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS WISTA LABORATORIES LTD. (SG) 2025-10-02 US claimed
US-20250275980-A1 METHYLTHIONINIUM SALT-CONTAINING COMPOSITIONS AND METHODS LOPEZ DARREN (US) 2025-09-04 US claimed
EP-4335517-B1 ADMINISTRATION AND DOSAGE OF DIAMINOPHENOTHIAZINES WISTA LAB LTD (SG) 2025-08-27 EP claimed
US-20250262219-A1 ADMINISTRATION AND DOSAGE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (SG) 2025-08-21 US claimed
US-20250222005-A1 METHYLENE BLUE CONTAINING COMPOUNDS FOR THE TREATMENT OF METHAEMOGLOBINAEMIA Wis Ta Laboratories Ltd. (SG) 2025-07-10 US claimed
EP-2645994-B1 FORMULATIONS COMPRISING METHYLTHIONINIUM CHLORIDE WISTA LAB LTD (SG) 2017-11-01 EP claimed
CN-106604728-A Compositions for photodynamic control of infection 普尔伯格有限公司 2017-04-26 CN claimed
EP-2480541-B1 CRYSTALLINE METHYLTHIONIUM CHLORIDE (METHYLENE BLUE) HYDRATES WISTA LAB LTD (SG) 2015-11-04 EP claimed
EP-2046767-B1 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVENCE TECHNOLOGIES (FR) 2015-04-22 EP claimed
EP-2457904-B1 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LAB LTD (SG) 2014-11-19 EP claimed
EP-2057136-B1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LAB LTD (SG) 2013-05-22 EP claimed
EP-1610829-B1 TISSUE-ADHESIVE FORMULATIONS TISSUEMED LTD (GB) 2010-01-20 EP claimed
EP-2046767-A2 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS Provence Technologies (FR) 2009-04-15 EP claimed
WO-2008006979-A2 PROCESS FOR PREPARING DIAMINOPHENOTHIAZINIUM COMPOUNDS PROVENCE TECHNOLOGIES (FR) 2008-01-17 WO claimed
US-4181128-A CONTACTING CONCURRENTLY WITH HYDROGEN PEROXIDE, OXYGEN, LIGHT AND ELECTRICITY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1980-01-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222005-A1 METHYLENE BLUE CONTAINING COMPOUNDS FOR THE TREATMENT OF METHAEMOGLOBINAEMIA MB, HBB, HMBS TSHR 4394/4885ACHE 3775/4885LMNA 746/4885
US-20260048066-A1 TREATMENT OF NEURODEGENERATIVE DISORDERS UTILISING METHYLTHIONINIUM (MT)-CONTAINING COMPOUNDS MAPT, PARK7, TARDBP TSHR 3126/4885ACHE 25/4885LMNA 3965/4885
US-20250275980-A1 METHYLTHIONINIUM SALT-CONTAINING COMPOSITIONS AND METHODS SLC6A12, TPMT, SLC6A5 TSHR 4311/4885ACHE 626/4885LMNA 1716/4885
US-20260115200-A1 Treatments Using Methylthioninium Salt, Liquid Mineral Blends, and/or Secondary Physiologically Active Compounds With Physiological Therapies TPMT, SLC6A6, SLC6A12 TSHR 2922/4885ACHE 135/4885LMNA 1461/4885
US-20250302843-A1 OPTIMISED DOSAGE OF DIAMINOPHENOTHIAZINES IN POPULATIONS MAPT, TPMT, LMTK2 TSHR 3363/4885ACHE 105/4885LMNA 1891/4885
US-20250262219-A1 ADMINISTRATION AND DOSAGE OF DIAMINOPHENOTHIAZINES ACHE, BCHE, PNMT TSHR 2540/4885ACHE 1/4885LMNA 4703/4885
US-20260083747-A1 COMPOSITIONS AND METHODS FOR SUPPORTING MITOCHONDRIAL HEALTH UQCRC2, UQCRC1, MT-ND2 TSHR 3769/4885ACHE 1715/4885LMNA 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.