SCHEMBL358469

SCHEMBL358469

CCOC(=O)c1cnn(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
GRN P28799 1/20 0.46
SORT1 Q99523 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
JMJD6 Q6NYC1 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20267444 0.86 LMNA (0.50) CYP2C19ESR1GRNSORT1SMN1; SMN2
SCHEMBL11130663 0.84 MKNK1 (0.53) CYP2C9CA12CA1CA2CA7
SCHEMBL3260386 0.83 SMN1; SMN2 (0.40) GRNSORT1SMN1; SMN2ALDH1A1LMNA
SCHEMBL25911751 0.81 L3MBTL1 (0.66) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL30004255 0.81 PIK3CD (0.43) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL21260188 0.81 CYP2C19 (0.46) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL6966096 0.81 CYP2C19 (0.46) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL21114971 0.81 CYP2C19 (0.46) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL3989230 0.81 CYP1A2 (0.47) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL3383513 0.81 ALDH1A1 (0.49) CYP2C9CYP2C19CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315433-A2 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics A.H. ROBINS COMPANY, INCORPORATED (US) 1989-05-10 EP claimed
US-12590108-B2 Boracic acid compound PHAENO THERAPEUTICS CO., LTD (CN) 2026-03-31 US disclosed
EP-4688778-A1 1H-PYRROLO[2,3-B]PYRIDIN-4-YL]-2-OXOPYRROLIDINE-3-CARBONITRILE DERIVATIVES AS TYROSINE KINASE 2 (TYK2) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES Biogen MA Inc. (US) 2026-02-11 EP disclosed
EP-4526298-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS F. Hoffmann-La Roche AG (CH) 2025-03-26 EP disclosed
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS HOFFMANN-LA ROCHE INC. (US) 2025-03-06 US disclosed
US-20250066369-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES NodThera Limited (GB) 2025-02-27 US disclosed
CN-119423103-A Herbicide composition for paddy field as well as preparation method and application thereof 浙江天一生物科技有限公司 2025-02-14 CN disclosed
CN-119264065-A Cell apoptosis inhibitor and preparation method and application thereof 中国科学院上海有机化学研究所 2025-01-07 CN disclosed
CN-119212989-A Pyrazole derivatives as STING agonists 豪夫迈·罗氏有限公司 2024-12-27 CN disclosed
EP-4460505-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES Nodthera Limited (GB) 2024-11-13 EP disclosed
US-5811411-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1998-09-22 US disclosed
US-5705513-A HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS MONSANTO COMPANY (US) 1998-01-06 US disclosed
US-5693667-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1997-12-02 US disclosed
US-5498630-A SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES MONSANTO COMPANY (US) 1996-03-12 US disclosed
CN-1087087-A The quinolinyloxadiazoles of weeding KOREA RES INST CHEM TECH (KR) 1994-05-25 CN disclosed
WO-1993007751-A1 FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1993-04-29 WO disclosed
EP-0538231-A1 Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1993-04-21 EP disclosed
US-5173496-A Antiinflammatory agents ICI PHARMA (FR) 1992-12-22 US disclosed
EP-0284174-B1 THERAPEUTIC PREPARATIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-29 EP disclosed
EP-0284174-A1 Therapeutic preparations IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066369-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES IL1B, NLRP3, IL1A CYP2C9 3090/4885CYP2C19 3249/4885CA12 4267/4885
US-12590108-B2 Boracic acid compound ME1, GPBAR1, BCL6 CYP2C9 943/4885CYP2C19 1450/4885CA12 134/4885
US-20250074913-A1 PYRAZOLE DERIVATIVES AS STING AGONISTS STING1, CGAS, MAVS CYP2C9 2903/4885CYP2C19 2218/4885CA12 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.