Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | TTPA | P49638 | 3/20 | 0.82 |
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | THRB | P10828 | 1/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.75 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | AKT1 | P31749 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Tocopherol SCHEMBL27697041 | 1.00 | LMNA (0.82) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL369660 | 1.00 | LMNA (0.82) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL28838443 | 1.00 | LMNA (0.82) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL28479098 | 1.00 | LMNA (0.82) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL358455 | 1.00 | LMNA (0.82) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL3950296 | 0.99 | LMNA (0.84) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL28434587 | 0.99 | LMNA (0.84) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL27697040 | 0.97 | LMNA (0.84) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL360251 | 0.97 | LMNA (0.84) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL25422940 | 0.96 | LMNA (0.76) | LMNATTPAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247405-A1 | METHODS AND COMPOSITIONS FOR NEUROPROTECTION | The Feinstein Institutes for Medical Research (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-4106828-A1 | POLYMER-ENCAPSULATED DRUG PARTICLES | GIE Medical, Inc. (US) | 2022-12-28 | — | — | EP | disclosed |
| WO-2022108963-A1 | METHODS AND COMPOSITIONS FOR NEUROPROTECTION | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2022-05-27 | — | — | WO | disclosed |
| CN-107080734-B | Emulsions comprising PEG derivatives of tocopherols | 维尔恩公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10668029-B2 | Compositions containing non-polar compounds | VIRUN, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| CN-110041270-A | A kind of preparation method of double semicarbazides pyrimidines in water phase | 广州臻莱迈新材料科技有限公司 | 2019-07-23 | — | — | CN | disclosed |
| US-10335385-B2 | Composition containing non-polar compounds | VIRUN, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| CN-105228470-B | Vitamin E soluble derivative preparation and composition comprising it | 维尔恩公司 | 2019-05-31 | — | — | CN | disclosed |
| US-10285971-B2 | Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same | VIRUN, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10220007-B2 | Compositions containing non-polar compounds | VIRUN, INC. (US) | 2019-03-05 | — | — | US | disclosed |
| CN-102036661-A | Vitamin derivatives and uses thereof | VIRUN INC | 2011-04-27 | — | — | CN | disclosed |
| CN-102036572-A | Emulsions comprising PEG derivatives of tocopherols | VIRUN INC | 2011-04-27 | — | — | CN | disclosed |
| EP-2268160-A1 | EMULSIONS INCLUDING A PEG-DERIVATIVE OF TOCOPHEROL | Virun, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2268274-A2 | VITAMIN E DERIVATIVES AND THEIR USES | Virun, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| US-20100041622-A1 | Compositions containing aminoalkanes and aminoalkane derivatives | VIRUN, INC. | 2010-02-18 | — | — | US | disclosed |
| WO-2010019255-A1 | COMPOSITIONS CONTAINING AMINOALKANES AND AMINOALKANE DERIVATIVES | VIRUN, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20090297665-A1 | Compositions containing non-polar compounds | VIRUN, INC. | 2009-12-03 | — | — | US | disclosed |
| US-20090297491-A1 | Compositions containing non-polar compounds | VIRUN, INC. | 2009-12-03 | — | — | US | disclosed |
| WO-2009117151-A2 | COMPOSITIONS CONTAINING NON-POLAR COMPOUNDS | VIRUN, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117152-A1 | EMULSIONS INCLUDING A PEG-DERIVATIVE OF TOCOPHEROL | VIRUN, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335385-B2 | Composition containing non-polar compounds | ELOVL6, ELOVL3, ELOVL1 | LMNA 302/4885TTPA 15/4885MAPT 1498/4885 |
| US-20100041622-A1 | Compositions containing aminoalkanes and aminoalkane derivatives | TAAR5, PDE3A, PDE2A | LMNA 1572/4885TTPA 750/4885MAPT 3026/4885 |
| US-10285971-B2 | Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same | TTPA, PTGES, HPGDS | LMNA 1169/4885TTPA 1/4885MAPT 1624/4885 |
| US-20090297491-A1 | Compositions containing non-polar compounds | ELOVL6, ELOVL3, ELOVL5 | LMNA 800/4885TTPA 117/4885MAPT 1511/4885 |
| US-10220007-B2 | Compositions containing non-polar compounds | ELOVL6, ELOVL3, ELOVL5 | LMNA 800/4885TTPA 117/4885MAPT 1511/4885 |
| US-10668029-B2 | Compositions containing non-polar compounds | ELOVL6, ELOVL3, ELOVL5 | LMNA 800/4885TTPA 117/4885MAPT 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.