Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.43 |
| ▸ | CA9 | Q16790 | 14/20 | 0.43 |
| ▸ | CA12 | O43570 | 13/20 | 0.43 |
| ▸ | CA1 | P00915 | 13/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365648 | 0.90 | CA9 (0.45) | CA2CA9CA12CA1EGFR | |
| SCHEMBL367707 | 0.87 | EGFR (0.44) | EGFRSRCHTR2AHTR2CAGTR1 | |
| SCHEMBL365427 | 0.85 | ALDH1A1 (0.48) | CA2CA9CA12CA1ALDH1A1 | |
| SCHEMBL366999 | 0.83 | EGFR (0.42) | EGFRSRCALDH1A1MAPT | |
| SCHEMBL366741 | 0.82 | EGFR (0.38) | CA2CA9CA12CA1EGFR | |
| SCHEMBL366104 | 0.82 | CA9 (0.46) | CA2CA9CA12CA1ALDH1A1 | |
| SCHEMBL367201 | 0.80 | EGFR (0.45) | EGFRSRCALDH1A1HTR2AHTR2C | |
| SCHEMBL367764 | 0.80 | EGFR (0.45) | EGFRSRCALDH1A1MAPTHTR2A | |
| SCHEMBL365259 | 0.78 | KDM4E (0.44) | EGFRSRCALDH1A1HTR2AHTR2C | |
| SCHEMBL364652 | 0.77 | CA2 (0.40) | CA2CA9CA12CA1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |