Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320721 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL29694512 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL932828 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL29442955 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL24631374 | 0.79 | LMNA (0.47) | KDM4EALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL30748245 | 0.79 | LMNA (0.47) | KDM4EALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL5700478 | 0.79 | TRIM24 (0.39) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL1972194 | 0.79 | SMN1; SMN2 (0.47) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL1379678 | 0.79 | PARP1 (0.56) | KDM4EALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL30040285 | 0.79 | PARP1 (0.56) | KDM4EALDH1A1TDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098353-A | A kind of colored thorn-like silica spheres and preparation method thereof | 温州大学 | 2017-08-29 | — | — | CN | claimed |
| JP-4066291-A | — | — | None | — | — | JP | disclosed |
| US-12509423-B2 | Compound, aldehyde dehydrogenase 2 activating agent, pharmaceutical composition, and therapeutic and/or prophylactic drug | ALCHEMEDICINE, INC. (JP) | 2025-12-30 | — | — | US | disclosed |
| US-20250049812-A1 | Compounds that Inhibit Necroptosis and Their Preparation Methods | SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) | 2025-02-13 | — | — | US | disclosed |
| EP-4403557-A1 | COMPOUND THAT INHIBITS PROGRAMMED CELL NECROSIS, AND PREPARATION METHOD THEREFOR | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2024-07-24 | — | — | EP | disclosed |
| US-20240109914-A1 | IMIDAZOTHIAZOLE COMPOUNDS AND ANALOGS THEREOF AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-04-04 | — | — | US | disclosed |
| US-20230295091-A1 | Compound, Aldehyde Dehydrogenase 2 Activating Agent, Pharmaceutical Composition, and Therapeutic and/or Prophylactic Drug | ALCHEMEDICINE, INC. (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-4238964-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | Alchemedicine, Inc. (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116348449-A | Compounds, acetaldehyde dehydrogenase 2 activators, pharmaceutical compositions, and therapeutic and/or prophylactic agents | 亚克医药株式会社 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023040818-A1 | COMPOUND THAT INHIBITS PROGRAMMED CELL NECROSIS, AND PREPARATION METHOD THEREFOR | 中国科学院上海有机化学研究所 | 2023-03-23 | — | — | WO | disclosed |
| US-8592629-B2 | Sulfonamide derivatives as Nav 1.7 inhibitors | PFIZER LIMITED (GB) | 2013-11-26 | — | — | US | disclosed |
| EP-2593432-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2013014060-A1 | SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-31 | — | — | WO | disclosed |
| US-20130029949-A1 | Substituted Quinolines and Their Use As Medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20130029949-A1 | Substituted Quinolines and Their Use As Medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20130029949-A1 | Substituted Quinolines and Their Use As Medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| WO-2013014060-A1 | SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-31 | — | — | WO | disclosed |
| WO-2012007861-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |
| US-20120010183-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
| JP-H0466291-A | CREAM SOLDER FOR PRINTING | UCHIHASHI ESTEC CO LTD | 1992-03-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509423-B2 | Compound, aldehyde dehydrogenase 2 activating agent, pharmaceutical composition, and therapeutic and/or prophylactic drug | ALDH2, ALDH1A1, ADH1A | KDM4E 3876/4885ALDH1A1 2/4885TDP1 1033/4885 |
| US-20230295091-A1 | Compound, Aldehyde Dehydrogenase 2 Activating Agent, Pharmaceutical Composition, and Therapeutic and/or Prophylactic Drug | ALDH2, ALDH1A1, ALDH3A1 | KDM4E 3044/4885ALDH1A1 2/4885TDP1 1591/4885 |
| US-20120010183-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | KDM4E 3227/4885ALDH1A1 1098/4885TDP1 1634/4885 |
| US-20240109914-A1 | IMIDAZOTHIAZOLE COMPOUNDS AND ANALOGS THEREOF AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS | NISCH, ABAT, ICMT | KDM4E 1875/4885ALDH1A1 2329/4885TDP1 3920/4885 |
| US-20250049812-A1 | Compounds that Inhibit Necroptosis and Their Preparation Methods | RIPK1, RIPK3, RIPK4 | KDM4E 1182/4885ALDH1A1 4793/4885TDP1 1415/4885 |
| US-20130029949-A1 | Substituted Quinolines and Their Use As Medicaments | QARS1, RECQL, CYP3A7 | KDM4E 2395/4885ALDH1A1 340/4885TDP1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.