Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | WNT3A | P56704 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL29216571 | 0.95 | PARP1 (0.54) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL158526 | 0.90 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL28189906 | 0.88 | RAB9A (0.53) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL4371075 | 0.88 | KDM4E (0.51) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL5070094 | 0.88 | KDM4E (0.51) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzophenone SCHEMBL20819440 | 0.86 | ALDH1A1 (0.73) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL16516335 | 0.86 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL8901469 | 0.86 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL9028632 | 0.84 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| Benzimidazole SCHEMBL10531809 | 0.84 | KDM4E (0.49) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102935230-A | Use of RNAi inhibiting PARP activtiy for the manufacture of a medicament for the treatment of cancer | UNIV SHEFFIELD | 2013-02-20 | — | — | CN | claimed |
| JP-4445553-B2 | — | — | 2010-04-07 | — | — | JP | claimed |
| US-7632591-B2 | Branched multiblock polybenzimidazole-benzamide copolymer and method for preparing the same, electrolyte membrane and paste/gel prepared therefrom | LG CHEM, LTD. (KR) | 2009-12-15 | — | — | US | claimed |
| EP-1819751-B1 | POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER, PROCESS FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE PREPARED THEREFROM AND PROCESS FOR PREPARING THE SAME | LG CHEMICAL LTD (KR) | 2009-07-01 | — | — | EP | claimed |
| JP-2008512561-A | — | — | 2008-04-24 | — | — | JP | claimed |
| WO-2007055459-A1 | BRANCHED MULTIBLOCK POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER AND METHOD FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE AND PASTE/GEL PREPARED THEREFROM | LG CHEM, LTD. (KR) | 2007-05-18 | — | — | WO | claimed |
| US-20070111075-A1 | Branched multiblock polybenzimidazole-benzamide copolymer and method for preparing the same, electrolyte membrane and paste/gel prepared therefrom | LG CHEM, LTD. (KR) | 2007-05-17 | — | — | US | claimed |
| US-11731946-B2 | Broad spectrum antivirulence, anti-persistence compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| CN-115125283-A | Method for screening quorum sensing inhibitor and determining action target point of quorum sensing inhibitor | 西北大学 | 2022-09-30 | — | — | CN | disclosed |
| US-20210130306-A1 | BROAD SPECTRUM ANTIVIRULENCE, ANTI-PERSISTENCE COMPOUNDS | THE GENERAL HOSPITAL CORPORATION | 2021-05-06 | — | — | US | disclosed |
| WO-2019079759-A1 | BROAD SPECTRUM ANTIVIRULENCE, ANTI-PERSISTENCE COMPOUNDS | RAHME LAURENCE (US) | 2019-04-25 | — | — | WO | disclosed |
| EP-2678319-B1 | ANTIBIOTIC TOLERANCE INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2019-04-17 | — | — | EP | disclosed |
| US-9643933-B2 | Compounds useful as antibiotic tolerance inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2017-05-09 | — | — | US | disclosed |
| WO-2007055459-A1 | BRANCHED MULTIBLOCK POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER AND METHOD FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE AND PASTE/GEL PREPARED THEREFROM | LG CHEM, LTD. (KR) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007055459-A1 | BRANCHED MULTIBLOCK POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER AND METHOD FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE AND PASTE/GEL PREPARED THEREFROM | LG CHEM, LTD. (KR) | 2007-05-18 | — | — | WO | disclosed |
| US-20070111075-A1 | Branched multiblock polybenzimidazole-benzamide copolymer and method for preparing the same, electrolyte membrane and paste/gel prepared therefrom | LG CHEM, LTD. (KR) | 2007-05-17 | — | — | US | disclosed |
| CN-1860155-A | Polybenzimidazole-benzamide copolymer, process for preparing the same, electrolyte membrane prepared therefrom and process for preparing the same | LG CHEMICAL LTD (KR) | 2006-11-08 | — | — | CN | disclosed |
| WO-2006062301-A1 | POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER, PROCESS FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE PREPARED THEREFROM AND PROCESS FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2006-06-15 | — | — | WO | disclosed |
| WO-2006062301-A1 | POLYBENZIMIDAZOLE-BENZAMIDE COPOLYMER, PROCESS FOR PREPARING THE SAME, ELECTROLYTE MEMBRANE PREPARED THEREFROM AND PROCESS FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2006-06-15 | — | — | WO | disclosed |
| US-20060068259-A1 | polymerizing 3,4-diaminobenzoic acid purified in the presence of nitrogen with p-aminobenzoic acid in polyphosphoric acid; placing solution on glass plate and hardening to form a film; removing the acid catalyst; fuel cell | LG CHEM, LTD. (KR) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731946-B2 | Broad spectrum antivirulence, anti-persistence compounds | ME2, ME1, ME3 | RAB9A 2775/4885SMN1; SMN2 1170/4885KDM4E 1362/4885 |
| US-20210130306-A1 | BROAD SPECTRUM ANTIVIRULENCE, ANTI-PERSISTENCE COMPOUNDS | ME2, ME1, ME3 | RAB9A 2775/4885SMN1; SMN2 1170/4885KDM4E 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.