Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263327 | 0.82 | TRPA1 (0.54) | ALDH1A1KMT2AMAPK1CASP3SENP7 | |
| SCHEMBL2202425 | 0.82 | TRPA1 (0.54) | ALDH1A1KMT2AMAPK1CASP3SENP7 | |
| SCHEMBL20587670 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRTP53PKMHTT | |
| SCHEMBL68148 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRTP53PKMHTT | |
| SCHEMBL6038454 | 0.79 | ADRA2A (0.56) | ALDH1A1HSD17B10KMT2ACYP2C9TSHR | |
| SCHEMBL28297389 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KMT2ATSHRMAPK1TP53 | |
| SCHEMBL6758498 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53PKMHTT | |
| SCHEMBL28787222 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53PKMHTT | |
| Ammonia Solution, Strong SCHEMBL2023211 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53PKMHTT | |
| Hydrochloric Acid SCHEMBL2362644 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238192-A1 | VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. | 2021-08-05 | — | — | US | disclosed |
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
| CN-108440299-A | A method of preparing 4- nitro benzophenone class compounds | 长沙理工大学 | 2018-08-24 | — | — | CN | disclosed |
| EP-2794620-B1 | BODIPY STRUCTURE FLUORESCENCE PROBES FOR DIVERSE BIOLOGICAL APPLICATIONS | NAT UNIV SINGAPORE (SG) | 2017-11-15 | — | — | EP | disclosed |
| US-8338362-B2 | Methods for controlling SR protein phosphorylation, and antiviral agents whose active ingredients comprise agents that control SR protein activity | MASATOSHI HAGIWARA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20120322814-A1 | METHODS OF INHIBITING IRE1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-20 | — | — | US | disclosed |
| US-8329728-B2 | Synthesis and anti-proliferative effect of substituted imidazo[4,5-c]pyridine compounds | SPELMAN COLLEGE (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120177572-A1 | AMYLOID IMAGING AS A SURROGATE MARKER FOR EFFICACY OF ANTI-AMYLOID THERAPIES | UNIVERSITY OF PITTSBURGH- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2012-07-12 | — | — | US | disclosed |
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095038-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
| US-7947723-B2 | Synthesis and anti-proliferative effect of benzimidazole derivatives | SPELMAN COLLEGE (US) | 2011-05-24 | — | — | US | disclosed |
| US-20100016359-A1 | METHODS FOR CONTROLLING SR PROTEIN PHOSPHORYLATION, AND ANTIVIRAL AGENTS WHOSE ACTIVE INGREDIENTS COMPRISE AGENTS THAT CONTROL SR PROTEIN ACTIVITY | MASATOSHI HAGIWARA | 2010-01-21 | — | — | US | disclosed |
| WO-2007038684-A2 | PYRROLE DERIVATIVES AS THERAPEUTIC COMPOUNDS | MYRIAD GENETICS, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| US-6743851-B2 | MIXTURE CONTAINING TETRAZOLE | NIPPON ZEON CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-6734248-B2 | CONTAINING A 1H-TETRAZOLE OR A 5,5'-BIS-1H-TETRAZOLE | NIPPON ZEON CO., LTD. (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-0822229-B1 | POLYIMIDE RESIN COMPOSITION | NIPPON ZEON CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-20020035196-A1 | Polyimide film | TANAKA AKIRA (JP) | 2002-03-21 | — | — | US | disclosed |
| US-20020032273-A1 | Pattern forming process using polyimide resin composition | TANAKA AKIRA (JP) | 2002-03-14 | — | — | US | disclosed |
| US-6310135-B1 | PHOTOSENSITIVE RESINS WITH TETRAZOLE COMPOUND | NIPPON ZEON CO., LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0822229-A1 | POLYIMIDE RESIN COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1998-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | TYMP, MKI67, CCNI | ALDH1A1 864/4885HSD17B10 4291/4885KMT2A 2479/4885 |
| US-20210238192-A1 | VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF | VCAM1, VAPB, ICAM1 | ALDH1A1 995/4885HSD17B10 4635/4885KMT2A 4790/4885 |
| US-20100016359-A1 | METHODS FOR CONTROLLING SR PROTEIN PHOSPHORYLATION, AND ANTIVIRAL AGENTS WHOSE ACTIVE INGREDIENTS COMPRISE AGENTS THAT CONTROL SR PROTEIN ACTIVITY | SRPK1, SRPK3, SRPK2 | ALDH1A1 4854/4885HSD17B10 2617/4885KMT2A 3810/4885 |
| US-20120177572-A1 | AMYLOID IMAGING AS A SURROGATE MARKER FOR EFFICACY OF ANTI-AMYLOID THERAPIES | TTR, APP, SAAL1 | ALDH1A1 2498/4885HSD17B10 2432/4885KMT2A 4494/4885 |
| US-20120322814-A1 | METHODS OF INHIBITING IRE1 | XBP1, DNAJC10, HSPA5 | ALDH1A1 3454/4885HSD17B10 1953/4885KMT2A 4299/4885 |
| US-20120095038-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | MKI67, CCNI, TYMP | ALDH1A1 949/4885HSD17B10 4139/4885KMT2A 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.