Ascorbic Acid

Ascorbic Acid

SCHEMBL3745

O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Na+]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ascorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.40
LMNA P02545 2/20 0.66
MAPT P10636 2/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
TYR P14679 2/20 0.41
MANBA O00462 1/20 0.40
HIF1A Q16665 1/20 0.40
HSPD1 P10809 1/20 0.36
HSPE1 P61604 1/20 0.36
TST Q16762 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ascorbic Acid SCHEMBL29351212 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL17141722 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL29598547 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL5165448 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL19378674 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL30301317 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL29350598 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL20839746 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL20788532 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL31277061 0.98 LMNA (0.64) LMNAMAPTL3MBTL1TYRMANBA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 116481 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075428-A Stable solid preparation 2026-05-26 CN claimed
CN-121587410-B Low-salt thick broad-bean sauce production process based on synergistic fermentation of composite strains Sichuan Dandan Pixian Bean Paste Group Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075668-A Composition and method for vancomycin oral liquid 2026-05-26 CN claimed
CN-122074696-A Buccal product and preparation method thereof 2026-05-26 CN claimed
CN-116903053-B Preparation process of magnesium doped modified nickel-iron-manganese based precursor material Hunan China Manganese Sodium Iron New Material Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121874958-B Antibacterial thermal insulation fiber based on thermal insulation material and preparation method thereof BOSIDENG DOWN WEAR Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075404-A Liquid formulations and methods for inhibiting pentetic acid degradation 2026-05-26 CN claimed
CN-122084902-A Method for enriching protein palmitoyl transferase substrate 2026-05-26 CN claimed
US-12642028-B2 Methods for wet atomic layer etching of tungsten TOKYO ELECTRON LIMITED (JP) 2026-05-26 US claimed
CN-121108418-B Waterproof and oilproof acrylate emulsion and preparation method and application thereof Zhongshan Bolimi New Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-4167562-A Method and composition for treating arteriosclerosis EVERS H RAY 1979-09-11 US claimed
US-4089983-A Color-stabilized semi-moist food and process THE QUAKER OATS COMPANY (US) 1978-05-16 US claimed
US-4081248-A ANTIDEPOSIT AGENTS THE B. F. GOODRICH COMPANY (US) 1978-03-28 US claimed
US-4058213-A Low temperature vapor phase sterilization and storage of biologically active injectable materials STONE IRWIN 1977-11-15 US claimed
US-4016292-A Process for improving the color stability of fresh meat HOOD DAVID EDWARD 1977-04-05 US claimed
US-4011348-A PROCESS FOR INHIBITING BROWNING OF FRUIT DIAMOND FRUIT GROWERS, INC. (US) 1977-03-08 US claimed
US-4001446-A PET FOODS THE QUAKER OATS COMPANY (US) 1977-01-04 US claimed
US-3973032-A ASCORBIC OR ERYTHORBIC ACID OR ALKALI METAL OR AMMONIUM SALTS BOARD OF REGENTS, STATE OF FLORIDA FOR AND ON BEHALF OF THE UNIVERSITY OF FLORIDA (US) 1976-08-03 US claimed
US-3958580-A Treatment of tobacco with ascorbic acid HOFFMANN-LA ROCHE INC. (US) 1976-05-25 US claimed
US-3956476-A X-RAYS, MEDICAL DIAGNOSIS SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-05-11 US claimed