Ascorbic Acid

Ascorbic Acid

SCHEMBL5165448

O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Na+].[Na+]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ascorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.40
LMNA P02545 2/20 0.66
MAPT P10636 2/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
TYR P14679 2/20 0.41
MANBA O00462 1/20 0.40
HIF1A Q16665 1/20 0.40
HSPD1 P10809 1/20 0.36
HSPE1 P61604 1/20 0.36
TST Q16762 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ascorbic Acid SCHEMBL29351212 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL17141722 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL29598547 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL3745 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL19378674 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL30301317 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL29350598 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL20839746 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL20788532 1.00 LMNA (0.66) LMNAMAPTL3MBTL1TYRMANBA
Ascorbic Acid SCHEMBL31277061 0.98 LMNA (0.64) LMNAMAPTL3MBTL1TYRMANBA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114947039-A Compound anticorrosive composition based on L-amino acid polyglycoside, and preparation method and application thereof 绥化市蓝源生物工程有限公司 2022-08-30 CN claimed
US-12485129-B2 Water soluble compositions comprising purified cannabinoids CANOPY GROWTH CORPORATION (CA) 2025-12-02 US disclosed
CN-119798562-A Polymer dispersing agent for paint and preparation method thereof 科之杰新材料集团有限公司 2025-04-11 CN disclosed
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed
US-20240261445-A1 PRECISION RADIOPHARMACEUTICAL THERAPY OF LYMPHOMA AND OTHER DISEASES WASHINGTON UNIVERSITY (US) 2024-08-08 US disclosed
CN-117279620-A Functionalized biocatalytic compositions 佩尔西奥制药公司 2023-12-22 CN disclosed
CN-114947039-A Compound anticorrosive composition based on L-amino acid polyglycoside, and preparation method and application thereof 绥化市蓝源生物工程有限公司 2022-08-30 CN disclosed
CN-114947039-A Compound anticorrosive composition based on L-amino acid polyglycoside, and preparation method and application thereof 绥化市蓝源生物工程有限公司 2022-08-30 CN disclosed
EP-3694477-A1 TOPICAL PRODUCTS WITH A BIPHASIC SYSTEM Cmed Aesthetics S.r.l. (IT) 2020-08-19 EP disclosed
WO-2019058249-A1 TOPICAL PRODUCTS WITH A BIPHASIC SYSTEM CMED AESTHETICS S.R.L. (IT) 2019-03-28 WO disclosed
EP-1768500-A1 COMPOSITIONS SUITABLE FOR TREATING CUTANEOUS SIGNS OF AGING Ferrosan A/S (DK) 2007-04-04 EP disclosed
WO-2006000226-A1 COMPOSITIONS SUITABLE FOR TREATING CUTANEOUS SIGNS OF AGING FERROSAN A/S (DK) 2006-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485129-B2 Water soluble compositions comprising purified cannabinoids CNR2, CNR1, PTGES THRB 3365/4885LMNA 2955/4885MAPT 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.