Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625857 | 0.85 | ALOX5 (0.41) | HTR7ALOX5ALDH1A1ALDH1A3 | |
| SCHEMBL3731249 | 0.80 | ALOX5 (0.35) | HSD17B10ALOX5ALDH1A1HPGDCACNA1C | |
| SCHEMBL30767224 | 0.70 | GRIA1 (0.38) | HTR7GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27034742 | 0.70 | GRIA1 (0.38) | HTR7GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3743379 | 0.69 | DRD2 (0.39) | ALDH1A1HPGD | |
| SCHEMBL14292117 | 0.64 | MEN1 (0.53) | HTR7ALDH1A1ITGB2ICAM1ITGAL | |
| SCHEMBL27780815 | 0.64 | MEN1 (0.35) | HTR7ALDH1A1GRIA1GRIA2GRIA3 | |
| SCHEMBL28094908 | 0.63 | GRIA1 (0.39) | ALDH1A1HPGDGRIA1GRIA2GRIA3 | |
| SCHEMBL23018314 | 0.62 | CYP2A6 (0.35) | ITGB2ICAM1ITGALMEN1KMT2A | |
| Ethane SCHEMBL2154693 | 0.62 | HSD17B10 (0.89) | HSD17B10PTGER4ALDH1A1ALDH1A3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | claimed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | claimed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1433469-B1 | Composition for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-10-11 | — | — | EP | claimed |
| EP-1434557-B1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-11-09 | — | — | EP | claimed |
| EP-1200050-B1 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2004-09-22 | — | — | EP | claimed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | claimed |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | US | disclosed |
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-12-10 | — | — | US | disclosed |
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | disclosed |
| US-7225920-B2 | Mixing device | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-05 | — | — | US | disclosed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20060002965-A1 | Mixing device | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) | 2006-01-05 | — | — | US | disclosed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | ASS1, SRM, COL1A1 | HSD17B10 453/4885PTGER4 1100/4885HTR7 1059/4885 |
| US-20060002965-A1 | Mixing device | TNF, EXOSC5, BMP6 | HSD17B10 2861/4885PTGER4 2607/4885HTR7 1429/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | HSD17B10 2392/4885PTGER4 3851/4885HTR7 2911/4885 |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | CCR3, CBR3, CCRL2 | HSD17B10 652/4885PTGER4 2362/4885HTR7 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.