SCHEMBL3752138

SCHEMBL3752138

CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 2/20 0.48
▸ CTSK P43235 2/20 0.48
▸ CTSB P07858 1/20 0.48
▸ CTSS P25774 1/20 0.48
▸ CAPN1 P07384 1/20 0.43
▸ AAK1 Q2M2I8 1/20 0.42
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA7 P43166 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ MAP1LC3B Q9GZQ8 1/20 0.40
▸ MAP1LC3A Q9H492 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ MEN1 O00255 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3752142 1.00 CTSL (0.48) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL12657499 1.00 CTSL (0.48) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL18206273 0.92 CTSL (0.44) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL18206276 0.92 CTSL (0.44) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL18206277 0.92 CTSL (0.44) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL23771861 0.89 CTSL (0.40) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL18916653 0.88 CTSK (0.42) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL18762624 0.88 CTSS (0.37) CTSLCTSKCTSBCTSSCAPN1
SCHEMBL10347068 0.87 CYP1A2 (0.38) CTSLCTSKCTSBCTSSCA1
SCHEMBL22199794 0.87 CTSK (0.46) CTSLCTSKCTSBCTSSCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186176-A Tengtoxin hapten, antigen, antibody, detection device and preparation and application thereof 广东科贸职业学院 2023-12-08 — — CN claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 — — US claimed
US-12612420-B2 Arginase inhibitors and methods of use thereof MOLECURE S.A. (PL) 2026-04-28 — — US disclosed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 — — US disclosed
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-02-12 — — US disclosed
US-12472165-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-11-18 — — US disclosed
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN THERAPEUTICS LTD (US) 2025-10-30 — — US disclosed
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-10-16 — — US disclosed
WO-2025108986-A1 2-AMINO-N-(OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2025-05-30 — — WO disclosed
US-12295942-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-05-13 — — US disclosed
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 — — US disclosed
EP-0169812-B1 PHOSPHATIDYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-08-23 — — EP disclosed
US-4788182-A VIRICIDES CIBA-GEIGY CORPORATION (US) 1988-11-29 — — US disclosed
EP-0186977-A2 Renin-inhibitory dipeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1986-07-09 — — EP disclosed
EP-0169812-A1 Phosphatidyl compounds, process for their preparation and their use CIBA-GEIGY AG (CH) 1986-01-29 — — EP disclosed
EP-0000063-B1 DIPEPTIDE DERIVATIVES OF 7-(N-ALPHA-SUBSTITUTED OR NON-SUBSTITUTED X-ARGINYL)-AMINO-4-METHYL-COUMARIN AJINOMOTO CO., INC. (JP) 1981-06-10 — — EP disclosed
US-4257939-A SUBSTRATES FOR DETERMINING ENZYME ACTIVITY AJINOMOTO CO., INC. (JP) 1981-03-24 — — US disclosed
US-4237047-A FLUORESCENT SUBSTRATE FOR MEASURING ENZYME ACTIVITY AJINOMOTO COMPANY, INCORPORATED (JP) 1980-12-02 — — US disclosed
US-4215047-A FLUOROGENIC SUBSTRATES FOR DETERMINING ENZYMATIC ACTIVITIES AJINOMOTO COMPANY INCORPORATED (JP) 1980-07-29 — — US disclosed
US-4064270-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 CTSL 145/4885CTSK 1499/4885CTSB 1236/4885
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSK 86/4885CTSB 44/4885
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ARG1, ARG2, PRMT1 CTSL 1464/4885CTSK 1677/4885CTSB 1102/4885
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE GFRA3, IL6ST, GFRA1 CTSL 164/4885CTSK 1659/4885CTSB 1425/4885
US-12472165-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSL 12/4885CTSK 586/4885CTSB 508/4885
US-12295942-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSL 12/4885CTSK 586/4885CTSB 508/4885
US-20250332148-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSL 12/4885CTSK 586/4885CTSB 508/4885
US-12612420-B2 Arginase inhibitors and methods of use thereof ARG1, ARG2, ARGLU1 CTSL 101/4885CTSK 1074/4885CTSB 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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