SCHEMBL3765131

SCHEMBL3765131

CCN1CCOc2ccc(O)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 3/20 0.46
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
AR P10275 1/20 0.41
KMT2A Q03164 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
GRM5 P41594 1/20 0.40
DRD3 P35462 4/20 0.39
DRD2 P14416 3/20 0.39
DRD4 P21917 2/20 0.39
DRD1 P21728 1/20 0.39
DRD5 P21918 1/20 0.39
CYP3A4 P08684 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
OPRM1 P35372 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL15020268 0.98 PTGER3 (0.45) PTGER3NR3C1PGRARKMT2A
SCHEMBL15521737 0.83 KMT2A (0.40) PTGER3KMT2ADRD3DRD2DRD4
SCHEMBL12347477 0.82 MAPT (0.47) PTGER3NR3C1PGRARKMT2A
SCHEMBL15516847 0.81 KMT2A (0.39) KMT2ADRD3DRD2DRD4DRD1
SCHEMBL16812271 0.81 KMT2A (0.39) ARKMT2ADRD3DRD2DRD4
SCHEMBL16812265 0.81 KMT2A (0.39) ARKMT2ADRD3DRD2DRD4
SCHEMBL15517316 0.81 KMT2A (0.39) ARKMT2ADRD3DRD2DRD4
SCHEMBL10228321 0.81 PTGER3 (0.43) PTGER3NR3C1PGRARKMT2A
SCHEMBL12347476 0.81 PTGER3 (0.46) PTGER3NR3C1PGRARKMT2A
SCHEMBL31167486 0.81 PTGER3 (0.43) PTGER3NR3C1PGRARKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102344-A2 NEAR INFRARED FLUOROPHORES FOR PERIPHERAL AND CENTRAL NERVE IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-05-15 WO disclosed
US-12605468-B2 Oxazine-based fluorophore compounds for nerve-specific imaging OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-04-21 US disclosed
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-05-11 US disclosed
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-05-11 US disclosed
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-05-11 US disclosed
EP-4093443-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING Oregon Health & Science University (US) 2022-11-30 EP disclosed
US-11492359-B2 Near-infrared nerve-sparing fluorophores OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-11-08 US disclosed
US-20210317137-A1 NEAR-INFRARED NERVE-SPARING FLUOROPHORES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2021-10-14 US disclosed
US-20210317137-A1 NEAR-INFRARED NERVE-SPARING FLUOROPHORES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2021-10-14 US disclosed
US-20210236657-A1 NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION OREGON HEALTH & SCIENCE UNIVERSITY (US) 2021-08-05 US disclosed
US-9233057-B2 Particular quinone direct dyes, dye composition comprising at least one such dye, implementation process therefor and use thereof L'OREAL (FR) 2016-01-12 US disclosed
US-20150166572-A1 HALOGENATED BENZOXAZINES AND THEIR USE EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2015-06-18 US disclosed
US-20150166572-A1 HALOGENATED BENZOXAZINES AND THEIR USE EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2015-06-18 US disclosed
US-20150166572-A1 HALOGENATED BENZOXAZINES AND THEIR USE EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2015-06-18 US disclosed
US-20140360523-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2014-12-11 US disclosed
US-20140360523-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2014-12-11 US disclosed
US-8679776-B2 Activatable dyes UNIVERSITY OF MASSACHUSETTS (US) 2014-03-25 US disclosed
WO-2014032732-A1 HALOGENATED BENZOXAZINES AND USE THEREOF EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) 2014-03-06 WO disclosed
WO-2013087770-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2013-06-20 WO disclosed
US-20100297684-A1 ACTIVATIBLE DYES UNIVERSITY OF MASSACHUSETTS 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492359-B2 Near-infrared nerve-sparing fluorophores NTRK1, PMP22, GAP43 PTGER3 918/4885NR3C1 3845/4885PGR 3679/4885
US-20210236657-A1 NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION PFAS, NPFFR2, NPFFR1 PTGER3 3379/4885NR3C1 4691/4885PGR 4442/4885
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING GAP43, NTRK1, CHAT PTGER3 3019/4885NR3C1 4454/4885PGR 4782/4885
US-20140360523-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF KRT18, SQOR, NDUFB7 PTGER3 3481/4885NR3C1 4345/4885PGR 2985/4885
US-20100297684-A1 ACTIVATIBLE DYES IK, MB, HMBS PTGER3 4870/4885NR3C1 4407/4885PGR 4720/4885
US-12605468-B2 Oxazine-based fluorophore compounds for nerve-specific imaging CHRNB2, CHRNB3, CHRNB4 PTGER3 1097/4885NR3C1 1368/4885PGR 4063/4885
US-20210317137-A1 NEAR-INFRARED NERVE-SPARING FLUOROPHORES NTRK1, NGF, SMN1; SMN2 PTGER3 1081/4885NR3C1 3720/4885PGR 3413/4885
US-20150166572-A1 HALOGENATED BENZOXAZINES AND THEIR USE XDH, BAZ1A, CYP4Z1 PTGER3 2688/4885NR3C1 1298/4885PGR 2231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.