Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732537 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6727323 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3767355 | 0.78 | MAPT (0.44) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL32665374 | 0.75 | CA2 (0.40) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3575927 | 0.75 | HTR6 (0.53) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3772307 | 0.75 | CA2 (0.45) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL32665057 | 0.75 | CA2 (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL24429431 | 0.73 | NSD2 (0.46) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2302323 | 0.72 | SIGMAR1 (0.51) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2893576 | 0.71 | NSD2 (0.50) | SMN1; SMN2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855166-B2 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20100317524-A1 | Sulfonylureas | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-1877386-A1 | HERBICIDALLY ACTIVE PHENYLSULPHONYL-UREA | Bayer CropScience AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| EP-1877380-A1 | SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-20060264329-A1 | Sulfonylureas | BAYER CROPSCIENCE GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1717232-A1 | Phenylsulfonylureas with herbicidal activity | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1717228-A1 | Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2006114221-A1 | SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2006-11-02 | — | — | WO | disclosed |
| WO-2006114220-A1 | HERBICIDALLY ACTIVE PHENYLSULPHONYL-UREA | BAYER CROPSCIENCE AG (DE) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317524-A1 | Sulfonylureas | IAPP, SLC5A2, SLC5A1 | SMN1; SMN2 1174/4885MAPT 4258/4885MEN1 1943/4885 |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | TST, CBR3, MYB | SMN1; SMN2 4458/4885MAPT 3054/4885MEN1 4650/4885 |
| US-20060264329-A1 | Sulfonylureas | INSR, FFAR3, GPR119 | SMN1; SMN2 952/4885MAPT 4837/4885MEN1 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.