SCHEMBL377130

SCHEMBL377130

CC(C)(C)[S-].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8309815 0.86 ALDH1A1 (0.31)
SCHEMBL7639404 0.86 TSHR (0.30)
SCHEMBL10500370 0.86
SCHEMBL11755774 0.86 TSHR (0.30)
Potassium Ion SCHEMBL5483411 0.86
SCHEMBL11253293 0.86 TSHR (0.30)
SCHEMBL17476390 0.86 TSHR (0.30)
SCHEMBL17476388 0.86
SCHEMBL10684443 0.86
Lithium Ion SCHEMBL6050085 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365507-B2 Diaryl sulfone compound, and manufacturing method for same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2016-06-14 US claimed
EP-2548860-A1 NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME Sumitomo Seika Chemicals CO. LTD. (JP) 2013-01-23 EP claimed
US-20130005982-A1 NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2013-01-03 US claimed
EP-1608704-B1 THIOPHOSPHINE COMPOUNDS AND METHOD OF MAKING POLYMERISABLE COMPOSITIONS CONTAINING THEM AND THEIR USE FOR MAKING OPHTALMIC LENSES ESSILOR INT (FR) 2008-03-19 EP claimed
EP-1392653-B1 A SHORT SYNTHESIS OF PYRIDINE-BASED PHARMACEUTICAL INTERMEDIATES WITH SULFUR-CONTAINING GROUPS AT THE 2- AND 3-POSITIONS UNIV NORTH CAROLINA STATE (US) 2007-08-15 EP claimed
US-6855825-B2 Short synthesis of pyridine-based pharmaceutical intermediates NORTH CAROLINA STATE UNIVERSITY (US) 2005-02-15 US claimed
CN-1533379-A Small synthesis of pyridine-based pharmaceutical intermediates containing sulfur in the 2-and 3-positions �Ϻ���ͨ��ѧ 2004-09-29 CN claimed
US-20040138463-A1 Short synthesis of pyridine-based pharmaceutical intermediates COMINS DANIEL L (US) 2004-07-15 US claimed
EP-1392653-A1 A SHORT SYNTHESIS OF PYRIDINE-BASED PHARMACEUTICAL INTERMEDIATES WITH SULFUR-CONTAINING GROUPS AT THE 2- AND 3-POSITIONS North Carolina State University (US) 2004-03-03 EP claimed
US-20030166941-A1 Short synthesis of pyridine-based pharmaceutical intermediates COMINS DANIEL L (US) 2003-09-04 US claimed
US-20020193606-A1 Short synthesis of pyridine-based pharmaceutical intermediates NORTH CAROLINA STATE UNIVERSITY 2002-12-19 US claimed
WO-2002096878-A1 A SHORT SYNTHESIS OF PYRIDINE-BASED PHARMACEUTICAL INTERMEDIATES WITH SULFUR-CONTAINING GROUPS AT THE 2- AND 3-POSITIONS NORTH CAROLINA STATE UNIVERSITY (US) 2002-12-05 WO claimed
US-20260118753-A1 ORGANOMETALLIC TIN PHOTORESISTS FOR EUV PHOTOLITHOGRAPHY LU FENG (US) 2026-04-30 US disclosed
WO-2025235874-A1 HETEROCYCLICS AS EGFR INHIBITORS SCHRÖDINGER, INC. (US) 2025-11-13 WO disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-20250277066-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-09-04 US disclosed
US-4841043-A Stereoselective synthesis of 1-β-alkyl carbapenem antibiotic intermediates BRISTOL-MYERS COMPANY (US) 1989-06-20 US disclosed
US-4311849-A SULFIDING, ESTERIFICATION CHEVRON RESEARCH (US) 1982-01-19 US disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed