Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082418 | 0.78 | MEN1 (0.42) | MEN1KMT2AOPRM1GRIN2DGRIN3B | |
| SCHEMBL24337423 | 0.75 | HTR2A (0.43) | KCNH2 | |
| SCHEMBL5082415 | 0.73 | MEN1 (0.39) | MEN1KMT2AOPRM1ALDH1A1OPRK1 | |
| SCHEMBL377463 | 0.68 | MEN1 (0.35) | MEN1KMT2AOPRL1 | |
| SCHEMBL6263640 | 0.67 | MEN1 (0.40) | MEN1KMT2AOPRM1GRIN2DGRIN3B | |
| SCHEMBL3310454 | 0.66 | MEN1 (0.46) | MEN1KMT2AOPRM1GRIN2DGRIN3B | |
| SCHEMBL5078420 | 0.66 | MEN1 (0.46) | MEN1KMT2AOPRM1GRIN2DGRIN3B | |
| SCHEMBL5080028 | 0.66 | MEN1 (0.46) | MEN1KMT2AOPRM1GRIN2DGRIN3B | |
| SCHEMBL9541911 | 0.66 | MEN1 (0.46) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11040986 | 0.64 | MEN1 (0.44) | MEN1KMT2AOPRM1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634171-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | F. Hoffmann-La Roche AG (CH) | 2025-10-22 | — | — | EP | claimed |
| US-20250313551-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | HOFFMANN-LA ROCHE INC. (US) | 2025-10-09 | — | — | US | claimed |
| EP-4585268-A2 | SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME | Twelve Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | claimed |
| US-12122788-B2 | Process of making CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-22 | — | — | US | claimed |
| CN-118530144-A | Paen Jia preparation method of beach | 中国医学科学院药物研究所 | 2024-08-23 | — | — | CN | claimed |
| WO-2024126634-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-20 | — | — | WO | claimed |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | INFINITY PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | claimed |
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2023-12-14 | — | — | US | claimed |
| CN-114075257-B | Method for preparing arylamine compound from On-DNA aryl halide | 成都先导药物开发股份有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116368134-A | Methods of making ubiquitin JAK inhibitors and related intermediate compounds | 施万生物制药研发IP有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116253606-A | Preparation method of aryl difluoromethyl alkyl sulfonyl fluoride compound | 上海应用技术大学 | 2023-06-13 | — | — | CN | claimed |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS, INC. | 2022-05-05 | — | — | US | claimed |
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 浙江省化工研究院有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-9233922-B2 | Process for producing N-(hetero)arylazoles | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-01-12 | — | — | US | claimed |
| WO-2012098044-A1 | PROCESS FOR THE PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)- 3-PHENYL PROPYLAMINE AND ITS SALTS STARTING FROM A NOVEL INTERMEDIATE | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2012-07-26 | — | — | WO | claimed |
| EP-2476665-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate | Cambrex Profarmaco Milano S.r.l. (IT) | 2012-07-18 | — | — | EP | claimed |
| US-20260148808-A1 | SYSTEM AND METHOD FOR OPTIMIZING CHEMICAL REACTIONS USING MACHINE LEARNING | MERCK PATENT GMBH (DE) | 2026-05-28 | — | — | US | disclosed |
| US-12630496-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2026-05-19 | — | — | US | disclosed |
| EP-1592698-A2 | PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF | Takasago International Corporation (JP) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072088-A2 | PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | CFTR, SLC26A4, TMEM109 | MEN1 2440/4885KMT2A 4522/4885OPRM1 1193/4885 |
| US-20260148808-A1 | SYSTEM AND METHOD FOR OPTIMIZING CHEMICAL REACTIONS USING MACHINE LEARNING | KIT, ALK, ACHE | MEN1 3621/4885KMT2A 273/4885OPRM1 1455/4885 |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885KMT2A 2333/4885OPRM1 2625/4885 |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885KMT2A 2333/4885OPRM1 2625/4885 |
| US-12122788-B2 | Process of making CFTR modulators | CFTR, SLC26A4, TMEM109 | MEN1 2440/4885KMT2A 4522/4885OPRM1 1193/4885 |
| US-20250313551-A1 | PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE | NQO2, SDHA, NDUFS3 | MEN1 3994/4885KMT2A 1193/4885OPRM1 1746/4885 |
| US-12630496-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | CRY1, NR1I2, GNA11 | MEN1 1976/4885KMT2A 3569/4885OPRM1 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.