Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082418 | 0.72 | MEN1 (0.42) | MEN1KMT2AOPRL1 | |
| SCHEMBL5082415 | 0.68 | MEN1 (0.39) | MEN1KMT2AOPRL1 | |
| SCHEMBL377365 | 0.68 | MEN1 (0.39) | MEN1KMT2AOPRL1 | |
| SCHEMBL4108492 | 0.66 | PDK2 (0.36) | — | |
| SCHEMBL29009347 | 0.64 | — | — | |
| SCHEMBL381944 | 0.62 | TRPA1 (0.31) | — | |
| SCHEMBL13649409 | 0.61 | PDK2 (0.33) | MEN1KMT2A | |
| SCHEMBL27789071 | 0.61 | PDK2 (0.36) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9541911 | 0.61 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL5078420 | 0.61 | MEN1 (0.46) | MEN1KMT2AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585268-A2 | SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME | Twelve Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | claimed |
| US-12122788-B2 | Process of making CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-22 | — | — | US | claimed |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | INFINITY PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | claimed |
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2023-12-14 | — | — | US | claimed |
| CN-116368134-A | Methods of making ubiquitin JAK inhibitors and related intermediate compounds | 施万生物制药研发IP有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| WO-2023057770-A1 | NANOPARTICLES FROM BACTERIA | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2023-04-13 | — | — | WO | claimed |
| CN-114716377-A | Process for producing pyrazole-amide compound | 日本烟草产业株式会社 | 2022-07-08 | — | — | CN | claimed |
| CN-109476609-B | Process for producing pyrazole-amide compound | 日本烟草产业株式会社 | 2022-06-14 | — | — | CN | claimed |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS, INC. | 2022-05-05 | — | — | US | claimed |
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 浙江省化工研究院有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-20260125363-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260103443-A1 | CHEMICAL COMPOUND | LMS CO LTD (KR) | 2026-04-16 | — | — | US | disclosed |
| EP-4186708-B1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING A LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM CORP (JP) | 2026-03-04 | — | — | EP | disclosed |
| US-20260049087-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS INC (US) | 2026-02-19 | — | — | US | disclosed |
| US-12473315-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2025-11-18 | — | — | US | disclosed |
| WO-2014081616-A1 | PREPARATION OF PRECURSORS FOR LEUKOTRIENE ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2014-05-30 | — | — | WO | disclosed |
| EP-2410380-B1 | Electrophotographic photoreceptor | TAKASAGO PERFUMERY CO LTD (JP) | 2013-10-02 | — | — | EP | disclosed |
| WO-2013032035-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-03-07 | — | — | WO | disclosed |
| US-20120022293-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2410380-A2 | Electrophotographic photoreceptor | Takasago International Corporation (JP) | 2012-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | CFTR, SLC26A4, TMEM109 | MEN1 2440/4885KMT2A 4522/4885SLC6A2 956/4885 |
| US-20260125363-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SLC26A4, SLC26A3 | MEN1 1794/4885KMT2A 3014/4885SLC6A2 205/4885 |
| US-20260049087-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PRKCB, PRKCD, PRKCA | MEN1 3619/4885KMT2A 4312/4885SLC6A2 1603/4885 |
| US-20120022293-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | SLC1A2, SLC18A2, SLC1A1 | MEN1 2771/4885KMT2A 620/4885SLC6A2 24/4885 |
| US-12473315-B2 | Polycyclic aromatic compound | PAH, ALK, AOC2 | MEN1 3441/4885KMT2A 723/4885SLC6A2 1011/4885 |
| US-20260103443-A1 | CHEMICAL COMPOUND | RAD51, CBR1, NOS1 | MEN1 4235/4885KMT2A 1418/4885SLC6A2 2111/4885 |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885KMT2A 2333/4885SLC6A2 3966/4885 |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885KMT2A 2333/4885SLC6A2 3966/4885 |
| US-12122788-B2 | Process of making CFTR modulators | CFTR, SLC26A4, TMEM109 | MEN1 2440/4885KMT2A 4522/4885SLC6A2 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.