SCHEMBL3775154

SCHEMBL3775154

Brc1ccc(-c2ccc(-c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA9 Q16790 3/20 0.56
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
ENPP3 O14638 1/20 0.47
ENPP1 P22413 1/20 0.47
PPARG P37231 6/20 0.44
PPARA Q07869 6/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
PPARD Q03181 1/20 0.44
MCL1 Q07820 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
CYP1A2 P05177 2/20 0.43
TNF P01375 1/20 0.43
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29490135 1.00 CA12 (0.56) CA12CA1CA2CA9HDAC8
SCHEMBL191382 0.98 HDAC8 (0.56) CA12CA1CA2CA9HDAC8
SCHEMBL29441251 0.98 HDAC8 (0.56) CA12CA1CA2CA9HDAC8
Bromide SCHEMBL28275806 0.96 HDAC8 (0.54) CA12CA1CA2CA9HDAC8
SCHEMBL24054594 0.90 CA12 (0.47) CA12CA1CA2CA9HDAC8
SCHEMBL15678825 0.90 CA12 (0.47) CA12CA1CA2CA9HDAC8
SCHEMBL28491556 0.90 HDAC8 (0.50) CA12CA1CA2CA9HDAC8
SCHEMBL12745114 0.89 HDAC8 (0.50) CA12CA1CA2CA9HDAC8
SCHEMBL30122908 0.89 CA12 (0.66) CA12CA1CA2CA9HDAC8
SCHEMBL10296325 0.89 CA12 (0.53) CA12CA1CA2CA9HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12490650-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-12-02 US disclosed
US-20240373746-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, And Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-11-07 US disclosed
US-20240217902-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2024-07-04 US disclosed
US-20240217902-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2024-07-04 US disclosed
US-12024526-B2 Fused polycyclic aromatic compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-07-02 US disclosed
US-12024526-B2 Fused polycyclic aromatic compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-07-02 US disclosed
US-11980087-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-05-07 US disclosed
US-11877508-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-01-16 US disclosed
US-11877508-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-01-16 US disclosed
US-20230345817-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2023-10-26 US disclosed
US-20100327230-A1 PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2010-12-30 US disclosed
US-20090284140-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed
WO-2009139358-A1 TRIARYLAMINE DERIVATIVE, LIGHT-EMITTING SUBSTANCE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-19 WO disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed
EP-1950194-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed
US-20080108811-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed
US-20080108811-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-28 US disclosed
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024526-B2 Fused polycyclic aromatic compound AHR, PAH, H1-2 CA12 2437/4885CA1 2403/4885CA2 718/4885
US-20240373746-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, And Electronic Device AHR, NAT1, TAAR1 CA12 4675/4885CA1 4716/4885CA2 4718/4885
US-20100327230-A1 PHENANTHRENE DERIVATIVE, AND MATERIAL FOR ORGANIC EL ELEMENT LEF1, AR, NR0B1 CA12 3124/4885CA1 2652/4885CA2 2860/4885
US-20090284140-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device AHR, NAT1, TAAR1 CA12 4675/4885CA1 4716/4885CA2 4718/4885
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, TYR, ALKBH3 CA12 3974/4885CA1 3385/4885CA2 2820/4885
US-20080108811-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same ALKBH2, ALKBH3, SETD1A CA12 3311/4885CA1 2626/4885CA2 2966/4885
US-20230345817-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC7A5, SLC43A1, SLCO4C1 CA12 4803/4885CA1 4874/4885CA2 4783/4885
US-11877508-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EMC1, EMC2, EPCAM CA12 956/4885CA1 1802/4885CA2 3219/4885
US-20240217902-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, AOC1 CA12 996/4885CA1 1591/4885CA2 3086/4885
US-12490650-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device AHR, NAT1, TAAR1 CA12 4675/4885CA1 4716/4885CA2 4718/4885
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same DDC, AOC2, ALKBH2 CA12 4036/4885CA1 3655/4885CA2 3778/4885
US-11980087-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device AHR, NAT1, TAAR1 CA12 4675/4885CA1 4716/4885CA2 4718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.