Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586692 | 0.88 | TDP1 (0.63) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL714123 | 0.82 | TDP1 (0.57) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL712632 | 0.81 | LMNA (0.61) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL4523401 | 0.81 | RAB9A (0.57) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL4655187 | 0.80 | TDP1 (0.59) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL582352 | 0.79 | TDP1 (0.63) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL194520 | 0.79 | TDP1 (0.63) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL557186 | 0.79 | TDP1 (0.63) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL7421565 | 0.78 | PTPN1 (0.53) | TDP1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL30150476 | 0.78 | LMNA (0.62) | TDP1ALDH1A1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-B1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20150307532-A1 | THIENOPYRIMIDINE INHIBITORS OF FARNESYL AND/OR GERANYLGERANYL PYROPHOSPHATE SYNTHASE | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2015-10-29 | — | — | US | disclosed |
| US-20150307532-A1 | THIENOPYRIMIDINE INHIBITORS OF FARNESYL AND/OR GERANYLGERANYL PYROPHOSPHATE SYNTHASE | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2015-10-29 | — | — | US | disclosed |
| WO-2014078957-A1 | THIENOPYRIMIDINE INHIBITORS OF FARNESYL AND/OR GERANYLGERANYL PYROPHOSPHATE SYNTHASE | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2014-05-30 | — | — | WO | disclosed |
| EP-1449923-B1 | NOVEL FORMATE DEHYDROGENASE TOLERANT TO HALOGEN COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | KANEKA CORP (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-7432095-B2 | Formate dehydrogenase tolerant to halogen compounds and process for producing the same | KANEKA CORPORATION (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432095-B2 | Formate dehydrogenase tolerant to halogen compounds and process for producing the same | KANEKA CORPORATION (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432095-B2 | Formate dehydrogenase tolerant to halogen compounds and process for producing the same | KANEKA CORPORATION (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20050064569-A1 | Novel formate dehydrogenase tolerant to halogen compounds and process for producing the same | KANEKA CORPORATION (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1449923-A1 | NOVEL FORMATE DEHYDROGENASE TOLERANT TO HALOGEN COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | KANEKA CORPORATION (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6682916-B2 | CHEMICAL INTERMEDIATE FOR DRUGS; REDUCTION USING ENZYME | KANEKA CORPORATION (JP) | 2004-01-27 | — | — | US | disclosed |
| EP-1298119-A1 | CHLOROHYDROXYACETONE DERIVATIVE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE CHLOROPROPANEDIOL DERIVATIVE FROM THE SAME | KANEKA CORPORATION (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020160398-A1 | Chlorohydroxyacetone derivative and process for producing optically active chloropropanediol derivative from the same | KANEKA CORPORATION (JP) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | TDP1 3318/4885ALDH1A1 2519/4885L3MBTL1 1817/4885 |
| US-20150307532-A1 | THIENOPYRIMIDINE INHIBITORS OF FARNESYL AND/OR GERANYLGERANYL PYROPHOSPHATE SYNTHASE | GGPS1, FDPS, FNTA | TDP1 1068/4885ALDH1A1 2029/4885L3MBTL1 2495/4885 |
| US-20050064569-A1 | Novel formate dehydrogenase tolerant to halogen compounds and process for producing the same | FDPS, IDH1, ADH4 | TDP1 302/4885ALDH1A1 218/4885L3MBTL1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.