SCHEMBL3843992

SCHEMBL3843992

CCOC(C)Oc1ccc(C=CC(=Cc2ccc(-c3ccc(C=CO)cc3)cc2)O[Si](C)(C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 5/20 0.35
TAS1R1 Q7RTX1 5/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
PTGS2 P35354 1/20 0.34
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
EED O75530 1/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838380 0.80 TRPM8 (0.32) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4866913 0.75 HDAC8 (0.34) TAS1R3TAS1R1HDAC3HDAC4HDAC1
SCHEMBL8898528 0.75 LTB4R (0.44) HDAC1HDAC2HDAC8BCHEACHE
SCHEMBL8898532 0.72 RELA (0.43) LTB4RLTB4R2MAPTNPC1RAB9A
SCHEMBL4059616 0.71 LMNA (0.46) PTGS2MAPTLMNA
SCHEMBL3838358 0.69 CA12 (0.43) TAS1R3TAS1R1BCHEACHEPTGS2
SCHEMBL7199294 0.69 LTB4R (0.41) LTB4RLTB4R2MAPTNPC1RAB9A
SCHEMBL4968520 0.69 FBP1 (0.33) TAS1R3TAS1R1BCHEACHEPTGS2
SCHEMBL3842067 0.69 LTB4R (0.41) LTB4RLTB4R2MAPTNPC1RAB9A
SCHEMBL7363804 0.69 PPARA (0.38) TAS1R3TAS1R1BCHEACHEPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 TAS1R3 874/4885TAS1R1 159/4885HDAC3 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.