Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cymene SCHEMBL3854468 | 1.00 | KEAP1 (0.40) | KEAP1NFE2L2CNR2LMNABCHE | |
| P-Cymene SCHEMBL7519316 | 0.99 | KEAP1 (0.40) | KEAP1NFE2L2CNR2LMNABCHE | |
| P-Cymene SCHEMBL29471131 | 0.95 | CNR2 (0.39) | KEAP1NFE2L2CNR2LMNABCHE | |
| P-Xylene SCHEMBL5417991 | 0.93 | LMNA (0.40) | KEAP1NFE2L2LMNAALDH1A1NPSR1 | |
| P-Xylene SCHEMBL5422594 | 0.93 | LMNA (0.40) | KEAP1NFE2L2LMNAALDH1A1NPSR1 | |
| Toluene SCHEMBL5421679 | 0.90 | DPP4 (0.39) | KEAP1NFE2L2LMNAACHEALDH1A1 | |
| Toluene SCHEMBL5430970 | 0.90 | DPP4 (0.39) | KEAP1NFE2L2LMNAACHEALDH1A1 | |
| Benzene SCHEMBL4859438 | 0.87 | DPP4 (0.45) | KEAP1CNR2LMNAALDH1A1NPSR1 | |
| Benzene SCHEMBL4865907 | 0.87 | DPP4 (0.45) | KEAP1CNR2LMNAALDH1A1NPSR1 | |
| P-Cymene SCHEMBL2240125 | 0.87 | ALDH1A1 (0.50) | CNR2LMNABCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | disclosed |
| EP-2868659-A1 | Method for producing optically active naphthalene compound | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-05-06 | — | — | EP | disclosed |
| EP-2749558-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-07-02 | — | — | EP | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7332622-B2 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2008-02-19 | — | — | US | disclosed |
| US-7268250-B2 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2007-09-11 | — | — | US | disclosed |
| EP-1308435-B1 | Process for producing optically active amino alcohols | KANTO KAGAKU (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1512678-A1 | Process for preparing optically active nitro compounds and cyano compounds | Kanto Kagaku Kabushiki Kaisha (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-20040176616-A1 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA | 2004-09-09 | — | — | US | disclosed |
| US-6696573-B1 | SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-02-24 | — | — | US | disclosed |
| US-6686505-B2 | HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1308435-A2 | Process for producing optically active amino alcohols | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1174426-A1 | METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | ADH1A, NOS1, ADH5 | KEAP1 2083/4885NFE2L2 945/4885CNR2 2238/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | KEAP1 232/4885NFE2L2 1607/4885CNR2 742/4885 |
| US-20040176616-A1 | Process for producing optically active compound | OSTC, NPEPPS, PPOX | KEAP1 3270/4885NFE2L2 1441/4885CNR2 4073/4885 |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | NOS1, NOS2, NOX1 | KEAP1 60/4885NFE2L2 40/4885CNR2 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.