Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | G6PD | P11413 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886237 | 0.83 | TRPM8 (0.49) | MAPTRXFP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3879707 | 0.82 | RAB9A (0.53) | MAPTRXFP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3873257 | 0.82 | ENPP2 (0.55) | MAPTRXFP1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3876863 | 0.80 | NR1H4 (0.49) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3872649 | 0.80 | ALDH1A1 (0.49) | LMNASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL3872157 | 0.79 | PPARG (0.45) | MAPTRXFP1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3872970 | 0.79 | ROCK2 (0.45) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3880937 | 0.78 | RAB9A (0.52) | MAPTLMNASMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3882723 | 0.78 | ALDH1A1 (0.51) | LMNASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL3882913 | 0.78 | LSS (0.48) | MAPTLMNASMN1; SMN2RAB9ASENP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | MAPT 4169/4885RXFP1 653/4885LMNA 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.