Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acifluorfen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | TTR | P02766 | 1/20 | 0.82 |
| ▸ | PPOX | P50336 | 1/20 | 0.82 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acifluorfen SCHEMBL30370086 | 1.00 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29352750 | 1.00 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29471425 | 1.00 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL10348484 | 0.98 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL8936622 | 0.96 | TDP1 (0.90) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL10495341 | 0.95 | MEN1 (0.77) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL10495355 | 0.94 | MEN1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL3690938 | 0.91 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10379343 | 0.91 | TDP1 (0.85) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL8028079 | 0.90 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7669 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060254-A1 | HERBICIDAL COMPOSITIONS | BAYER AG (DE) | 2026-03-05 | — | — | US | claimed |
| US-20260020563-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-01-22 | — | — | US | claimed |
| US-20260007133-A1 | HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS | BASF SE (DE) | 2026-01-08 | — | — | US | claimed |
| US-20250374920-A1 | HERBICIDAL COMPOSITION COMPRISING ALKYL POLYGLYCOSIDES | BASF SE (DE) | 2025-12-11 | — | — | US | claimed |
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| US-20250318528-A1 | HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-10-16 | — | — | US | claimed |
| US-12376586-B2 | Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof | BASF Agro B.V. (NL) | 2025-08-05 | — | — | US | claimed |
| US-20250241298-A1 | Liquid Sulfonylurea-Containing Herbicidal Compositions | BATTELLE UK LIMITED (GB) | 2025-07-31 | — | — | US | claimed |
| US-20250230462-A1 | PPO2 POLYPEPTIDE HAVING TOLERANCE TO PPO INHIBITOR HERBICIDE AND APPLICATION | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2025-07-17 | — | — | US | claimed |
| EP-4577047-A1 | HERBICIDAL COMPOSITIONS | Bayer Aktiengesellschaft (DE) | 2025-07-02 | — | — | EP | claimed |
| EP-0212200-A2 | Pyridine derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-03-04 | — | — | EP | claimed |
| EP-0207653-A1 | Herbicidal compositions comprising microbial herbicides and chemical herbicides or plant growth regulators | THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 1987-01-07 | — | — | EP | claimed |
| CN-86100691-A | The Herbicidal mixture of N-((phosphonomethyl) glycyl) sulfonamide type compound | — | 1986-12-03 | — | — | CN | claimed |
| EP-0182120-A2 | Herbicidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0138945-A4 | GLYPHOSATE-TYPE HERBICIDAL COMPOSITIONS. | CHEVRON RES (US) | 1985-09-09 | — | — | EP | claimed |
| EP-0080312-B1 | THE PREPARATION OF CERTAIN DIPHENYL ETHERS ESPECIALLY 5-(4-TRIFLUOROMETHYLPHENOXY)- AND 5-(2-HALO-4-TRIFLUOROMETHYLPHENOXY)-2-NITROBENZOIC ACID AND SALTS AND ESTERS AND AMIDES | ROHM AND HAAS COMPANY (US) | 1985-05-29 | — | — | EP | claimed |
| EP-0138945-A1 | GLYPHOSATE-TYPE HERBICIDAL COMPOSITIONS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-05-02 | — | — | EP | claimed |
| WO-1984003607-A1 | GLYPHOSATE-TYPE HERBICIDAL COMPOSITIONS | CHEVRON RES (US) | 1984-09-27 | — | — | WO | claimed |
| US-4395570-A | CONDENSATION OF 4-TRIFLUOROMETHYLPHENOL WITH 1-HAL-4-SUBSTITUTED-4-NITROBENZENE, THEN HALOGENATION | ROHM AND HAAS COMPANY (US) | 1983-07-26 | — | — | US | claimed |
| EP-0080312-A1 | The preparation of certain diphenyl ethers especially 5-(4-trifluoromethylphenoxy)- and 5-(2-halo-4-trifluoromethylphenoxy)-2-nitrobenzoic acid and salts and esters and amides | ROHM AND HAAS COMPANY (US) | 1983-06-01 | — | — | EP | claimed |