Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 16/20 | 0.36 |
| ▸ | CA2 | P00918 | 16/20 | 0.36 |
| ▸ | CA9 | Q16790 | 15/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA7 | P43166 | 5/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.34 |
| ▸ | CA3 | P07451 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA6 | P23280 | 4/20 | 0.34 |
| ▸ | CA5A | P35218 | 4/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982470 | 0.98 | TSHR (0.62) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL1118647 | 0.96 | USP2 (0.58) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL3979004 | 0.86 | USP2 (0.50) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| Busulfan SCHEMBL4373 | 0.81 | TSHR (1.00) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| Busulfan SCHEMBL4764696 | 0.81 | TSHR (1.00) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2166634 | 0.80 | TSHR (0.68) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL1606138 | 0.78 | TSHR (0.65) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL4952202 | 0.78 | TSHR (0.94) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| Busulfan SCHEMBL7195165 | 0.78 | TSHR (0.94) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL4954793 | 0.78 | TSHR (0.94) | TSHRKDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608308-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| CN-107879960-B | Lipids and lipid compositions for delivery of active ingredients | 诺华股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2020-10-06 | — | — | US | disclosed |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2020-10-06 | — | — | US | disclosed |
| US-10729775-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2020-08-04 | — | — | US | disclosed |
| EP-3608308-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2020-02-12 | — | — | EP | disclosed |
| EP-2964608-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2019-08-28 | — | — | EP | disclosed |
| US-10230121-B2 | Copolymers comprising crosslinkable protogenic groups which can be used to constitute fuel cell membranes | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2019-03-12 | — | — | US | disclosed |
| US-20180369386-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2018-12-27 | — | — | US | disclosed |
| US-10124065-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2018-11-13 | — | — | US | disclosed |
| US-7371493-B2 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-05-13 | — | — | US | disclosed |
| US-7364825-B2 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-29 | — | — | US | disclosed |
| US-7351508-B2 | Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-01 | — | — | US | disclosed |
| US-7344811-B2 | Polysilane-based charge transport materials | SAMSUNG ELECTRONIC CO., LTD. (KR) | 2008-03-18 | — | — | US | disclosed |
| US-20060210897-A1 | Charge transport materials having at least a metallocene group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-09-21 | — | — | US | disclosed |
| US-20060204875-A1 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-09-14 | — | — | US | disclosed |
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-08-10 | — | — | US | disclosed |
| US-20060166118-A1 | Heterocycle-hydrazone based charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-07-27 | — | — | US | disclosed |
| US-20060093933-A1 | Polysilane-based charge transport materials | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-05-04 | — | — | US | disclosed |
| US-20060078351-A1 | Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166118-A1 | Heterocycle-hydrazone based charge transport materials | AQP1, SLC9B2, SLC9A2 | TSHR 1662/4885KDM4E 2960/4885USP2 4818/4885 |
| US-10124065-B2 | Lipids and lipid compositions for the delivery of active agents | LIPA, LPAR1, LPAR4 | TSHR 1112/4885KDM4E 2406/4885USP2 4628/4885 |
| US-20180369386-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, LPAR1, LPAR4 | TSHR 1112/4885KDM4E 2406/4885USP2 4628/4885 |
| US-20060204875-A1 | Charge transport materials having a 1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl group | TSPO, SLC43A1, LMNB2 | TSHR 4024/4885KDM4E 488/4885USP2 4493/4885 |
| US-20060177750-A1 | Charge transport materials having a nitrogen-containing-heterocycle hydrazone group | SLC1A2, SLC9B2, SLC6A19 | TSHR 3280/4885KDM4E 3676/4885USP2 4837/4885 |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | LIPA, LPAR1, LPAR4 | TSHR 1112/4885KDM4E 2406/4885USP2 4628/4885 |
| US-10729775-B2 | Lipids and lipid compositions for the delivery of active agents | LIPA, LPAR1, LPAR4 | TSHR 1112/4885KDM4E 2406/4885USP2 4628/4885 |
| US-20060078351-A1 | Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups | SLC16A7, SLC16A1, SLC16A3 | TSHR 1823/4885KDM4E 2185/4885USP2 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.