Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 5/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14350865 | 0.82 | PKM (0.52) | PKMALDH1A1USP2KEAP1NFE2L2 | |
| SCHEMBL6487444 | 0.79 | AGER (0.52) | KEAP1NFE2L2GAACA1CA2 | |
| SCHEMBL5622693 | 0.75 | ESR1 (0.54) | PKMALDH1A1USP2KEAP1NFE2L2 | |
| SCHEMBL691734 | 0.75 | ALDH1A1 (0.73) | PKMALDH1A1KEAP1NFE2L2PGR | |
| SCHEMBL10449139 | 0.72 | PKM (0.57) | PKMALDH1A1KEAP1NFE2L2PGR | |
| SCHEMBL4195254 | 0.71 | PKM (0.61) | PKMALDH1A1MMP13MMP1MMP2 | |
| SCHEMBL10872609 | 0.70 | PKM (0.55) | PKMALDH1A1KEAP1NFE2L2PGR | |
| SCHEMBL4204765 | 0.70 | LMNA (0.76) | PKMALDH1A1KEAP1MMP13MMP1 | |
| SCHEMBL5622356 | 0.70 | PGR (0.79) | PKMALDH1A1KEAP1NFE2L2PGR | |
| SCHEMBL3615482 | 0.70 | BMP1 (0.55) | PKMKEAP1MMP13MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062036-A2 | PROCESSES FOR PREPARING LEVOCETIRIZINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-05-14 | — | — | WO | disclosed |