Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL30951754 | 0.93 | POLB (0.58) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL4111621 | 0.90 | POLB (0.63) | TSHRCES1KMT2APKMCA1 | |
| Tert-Butanol SCHEMBL9101844 | 0.90 | TSHR (0.51) | TSHRCES1KMT2APKMCA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL29284789 | 0.86 | POLB (0.51) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL7297660 | 0.85 | TSHR (0.55) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL254773 | 0.83 | CES1 (0.65) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL1436249 | 0.83 | CES1 (0.65) | TSHRCES1KMT2APKMCA1 | |
| Methylamine SCHEMBL29169653 | 0.82 | TSHR (0.60) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL248294 | 0.82 | TSHR (0.64) | TSHRCES1KMT2APKMCA1 | |
| SCHEMBL11527677 | 0.81 | TSHR (0.63) | TSHRCES1KMT2APKMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630421-A1 | SYNTHESIS OF SULFOXIMINE COMPOUNDS HAVING A STEREOGENIC SULFUR ATOM | Syngenta Crop Protection AG (CH) | 2025-10-15 | — | — | EP | claimed |
| CN-119350315-A | 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof | 南开大学 | 2025-01-24 | — | — | CN | claimed |
| WO-2024121335-A1 | SYNTHESIS OF SULFOXIMINE COMPOUNDS HAVING A STEREOGENIC SULFUR ATOM | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-13 | — | — | WO | claimed |
| CN-122070135-A | Pharmaceutical compositions and methods of use thereof | 托特斯医药公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20260132136-A1 | Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 | BOEHRINGER INGELHEIM INT GMBH (DE) | 2026-05-14 | — | — | US | disclosed |
| US-12612407-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist | BEONE MEDICINES I GMBH (CH) | 2026-04-28 | — | — | US | disclosed |
| US-20260109698-A1 | MALT-1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2026-04-23 | — | — | US | disclosed |
| EP-4724425-A1 | SYNTHESIS OF ENANTIOENRICHED 2-CYANO PYRIDYL SULFOXIDES | Syngenta Crop Protection AG (CH) | 2026-04-15 | — | — | EP | disclosed |
| US-12595265-B2 | Inhibitors of activin receptor-like kinase | BLUEPRINT MEDICINES CORPORATION (US) | 2026-04-07 | — | — | US | disclosed |
| US-12590096-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists | BeOne Medicines | GmbH (CH) | 2026-03-31 | — | — | US | disclosed |
| WO-2026046899-A1 | PYRAZOLO[5,1-f][1,2,4]TRIAZIN-4-ONES AS INHIBITORS OF NOX4 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2026-03-05 | — | — | WO | disclosed |
| US-20070185106-A1 | Pyrrole derivatives as gonadotropin releasing hormone (gnrh) antagonists | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
| US-20070167428-A1 | Thienopyrroles as antagonists of gnrh | ASTRAZENECA AB (SE) | 2007-07-19 | — | — | US | disclosed |
| US-20070167428-A1 | Thienopyrroles as antagonists of gnrh | ASTRAZENECA AB (SE) | 2007-07-19 | — | — | US | disclosed |
| CN-1809570-A | [1,2,4] triazolo [1, 5-a ] pyrimidin-2-ylurea derivatives and uses thereof | NIPPON KAYAKU KK (JP) | 2006-07-26 | — | — | CN | disclosed |
| EP-0044696-B1 | 5-OXO-2,5,-DIHYDRO-1,2,4-TRIAZINES, METHODS FOR THEIR PRODUCTION, HERBICIDAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4451283-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0044696-A2 | 5-Oxo-2,5,-dihydro-1,2,4-triazines, methods for their production, herbicidal compositions comprising them, and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4273721-A | Tertiary amine polyalkylene glycol esters, their addition salts and their quaternary ammonium compounds | BRISTOL-MYERS COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4237305-A | INTERMEDIATES FOR PREPARING NEW ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185106-A1 | Pyrrole derivatives as gonadotropin releasing hormone (gnrh) antagonists | GNRHR, PRLHR, GHRHR | TSHR 26/4885CES1 3711/4885KMT2A 1732/4885 |
| US-12612407-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist | TLR7, TLR8, TLR1 | TSHR 68/4885CES1 979/4885KMT2A 1437/4885 |
| US-20260132136-A1 | Pyrazolo[5,1-f][1,2,4]triazin-4-ones as inhibitors of NOX4 | NOX4, NOX1, NOX3 | TSHR 1221/4885CES1 415/4885KMT2A 2820/4885 |
| US-20070167428-A1 | Thienopyrroles as antagonists of gnrh | GNRHR, PRLHR, TRHR | TSHR 9/4885CES1 3689/4885KMT2A 1902/4885 |
| US-12595265-B2 | Inhibitors of activin receptor-like kinase | ACVR1, ACVRL1, ACVR2A | TSHR 126/4885CES1 623/4885KMT2A 3475/4885 |
| US-12590096-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists | TLR8, TLR7, TLR1 | TSHR 143/4885CES1 1739/4885KMT2A 929/4885 |
| US-20260109698-A1 | MALT-1 MODULATORS | MALT1, BCL6, BCL3 | TSHR 2213/4885CES1 626/4885KMT2A 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.