Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.45 |
| ▸ | SCARB1 | Q8WTV0 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541977 | 0.81 | RORC (0.59) | RORCSCARB1HRH1HTR6PTGER4 | |
| SCHEMBL4209635 | 0.79 | MAOA (0.48) | HRH1HTR6PTGER4KDM4ERAB9A | |
| SCHEMBL4024468 | 0.77 | ALDH1A1 (0.55) | RORCPTGER4KDM4ERAB9A | |
| SCHEMBL4029830 | 0.74 | SCARB1 (0.46) | RORCSCARB1PTGER4KDM4E | |
| SCHEMBL21076080 | 0.73 | RORC (0.52) | RORCPTGER4KDM4ESLC6A4 | |
| SCHEMBL28972487 | 0.68 | LMNA (0.45) | SCARB1KDM4ERAB9A | |
| SCHEMBL30061980 | 0.68 | LMNA (0.45) | SCARB1KDM4ERAB9A | |
| SCHEMBL28972120 | 0.67 | NPC1 (0.47) | KDM4ERAB9APOLB | |
| SCHEMBL29643208 | 0.67 | PTGER4 (0.63) | RORCPTGER4KDM4EPOLB | |
| SCHEMBL5892136 | 0.67 | PTGER4 (0.63) | RORCPTGER4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |