Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047771 | 0.92 | CTSK (0.39) | CTSKCHRNA7ELANEEPHX1 | |
| SCHEMBL4045179 | 0.91 | CTSK (0.44) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4041149 | 0.90 | ITGA4 (0.39) | CTSKCHRNA7 | |
| SCHEMBL4049549 | 0.89 | GPR132 (0.38) | CTSKCTSSCTSBCHRNA7EPHX1 | |
| SCHEMBL4048929 | 0.89 | CTSK (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4045035 | 0.89 | CTSK (0.45) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4040214 | 0.89 | GPR132 (0.39) | CTSKCHRNA7 | |
| SCHEMBL4049343 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4050440 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4042165 | 0.88 | EPHX1 (0.37) | CTSKCTSLCTSSCTSBCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |