Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045083 | 0.92 | CTSK (0.47) | CTSKCHRNA7EPHX1ELANE | |
| SCHEMBL4043031 | 0.91 | HTRA1 (0.37) | CTSKCHRNA7ACACBGPR132 | |
| SCHEMBL4041149 | 0.89 | ITGA4 (0.39) | CTSKCHRNA7ECE1 | |
| SCHEMBL4047976 | 0.89 | CTSK (0.43) | CTSK | |
| SCHEMBL4044586 | 0.89 | CTSK (0.37) | CTSKCHRNA7GPR132SIGMAR1 | |
| SCHEMBL4045728 | 0.89 | CTSK (0.35) | CTSKCHRNA7ACACBGPR132 | |
| SCHEMBL4049549 | 0.89 | GPR132 (0.38) | CTSKCHRNA7EPHX1GPR132ECE1 | |
| SCHEMBL4040981 | 0.89 | CTSK (0.35) | CTSKCHRNA7ACACBGPR132 | |
| SCHEMBL4040214 | 0.88 | GPR132 (0.39) | CTSKCHRNA7GPR132ECE1 | |
| SCHEMBL4044443 | 0.88 | ALDH1A1 (0.38) | CTSKACACBGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689720-B1 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2009-04-15 | — | — | EP | disclosed |