Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757691 | 0.87 | GPR119 (0.43) | PDE4B | |
| SCHEMBL4051573 | 0.84 | CCR5 (0.41) | RBP4MEN1KMT2A | |
| SCHEMBL4050230 | 0.78 | PDE4B (0.45) | PDE4BMEN1KMT2A | |
| SCHEMBL4051411 | 0.78 | RBP4 (0.37) | RBP4GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4373911 | 0.77 | CLK4 (0.42) | RBP4PDE4BMEN1KMT2A | |
| SCHEMBL4056993 | 0.75 | PARP10 (0.45) | RBP4FFAR4 | |
| SCHEMBL4051853 | 0.75 | GPR119 (0.44) | RBP4TRPC6 | |
| SCHEMBL4052435 | 0.73 | GPR119 (0.42) | FFAR4 | |
| SCHEMBL4058702 | 0.73 | SLC6A9 (0.49) | — | |
| SCHEMBL4052686 | 0.73 | TRPC6 (0.42) | PDE4BTRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |