Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051965 | 0.94 | MC4R (0.38) | ALDH1A1CTSKMC4RMC3RMC1R | |
| SCHEMBL4039893 | 0.93 | CTSK (0.41) | ALDH1A1CTSKPREPFAPRAB9A | |
| SCHEMBL4046989 | 0.90 | ALDH1A1 (0.38) | ALDH1A1PPARGPPARAPREPFAP | |
| SCHEMBL4043678 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CTSKPPARGPPARAPREP | |
| SCHEMBL4047431 | 0.89 | ALDH1A1 (0.37) | ALDH1A1PPARGPPARAPREPFAP | |
| SCHEMBL4043596 | 0.88 | ELANE (0.38) | ALDH1A1CTSKPREPFAPMC4R | |
| SCHEMBL4043124 | 0.87 | POLB (0.34) | ALDH1A1CTSKRAB9AELANELMNA | |
| SCHEMBL4043183 | 0.86 | CTSK (0.43) | ALDH1A1CTSKPREPFAPMC4R | |
| SCHEMBL4046799 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CTSKPREPFAP | |
| SCHEMBL4045687 | 0.86 | MC4R (0.34) | ALDH1A1CTSKPREPFAPMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |