Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075668 | 0.78 | KDM4E (0.43) | HRH1LMNASLC5A2KDM4EPOLB | |
| SCHEMBL9246163 | 0.75 | ALDH1A1 (0.42) | HRH1LMNAKDM4EPOLBNPSR1 | |
| SCHEMBL146503 | 0.66 | CYP1A2 (0.56) | LMNAKDM4EPOLBGAAALDH1A1 | |
| SCHEMBL29507760 | 0.65 | CYP3A4 (0.62) | HRH1LMNASLC5A2KDM4EPOLB | |
| SCHEMBL6695468 | 0.65 | CYP3A4 (0.62) | HRH1LMNASLC5A2KDM4EPOLB | |
| SCHEMBL11667512 | 0.64 | LMNA (0.42) | HRH1LMNASLC5A2KDM4EPOLB | |
| SCHEMBL2163308 | 0.63 | PKM (0.68) | LMNAKDM4EPOLBNPSR1GAA | |
| SCHEMBL2544770 | 0.63 | MEN1 (0.35) | HRH1LMNAKDM4EPOLBNPSR1 | |
| SCHEMBL1176401 | 0.62 | LMNA (0.36) | LMNAKDM4EPOLBNPSR1GAA | |
| SCHEMBL11780734 | 0.61 | LMNA (0.48) | LMNAKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981833-A | Heat sensitive recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | claimed |
| US-11130737-B2 | Multifunctional aminoquinoline therapeutic agents | LOHOCLA RESEARCH CORPORATION (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200095204-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | LOHOCLA RESEARCH CORPORATION | 2020-03-26 | — | — | US | disclosed |
| US-10435371-B2 | Multifunctional aminoquinoline therapeutic agent | LOHOCLA RESEARCH CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| US-10391088-B2 | Analgesic compositions | LOHOCLA RESEARCH CORPORATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190099412-A1 | ANALGESIC COMPOSITIONS | LOHOCLA RESEARCH CORPORATION | 2019-04-04 | — | — | US | disclosed |
| US-20190092731-A1 | MULTIFUNCAIONAL AMINOQUINOLINE THERAPEUTIC AGENT | LOHOCLA RESEARCH CORPORATION | 2019-03-28 | — | — | US | disclosed |
| US-10112905-B2 | Multifunctional aminoquinoline therapeutic agents | LOHOCLA RESEARCH CORPORATION (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170204064-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | LOHOCLA RESEARCH CORPORATION | 2017-07-20 | — | — | US | disclosed |
| US-20090227652-A1 | INDOLE DERIVATIVES AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1863762-A4 | INDOLE DERIVATIVES AND METHODS OF USING THE SAME | UNIV COLORADO (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-1863762-A1 | INDOLE DERIVATIVES AND METHODS OF USING THE SAME | The Regents of the University of Colorado (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006098884-A1 | INDOLE DERIVATIVES AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2006-09-21 | — | — | WO | disclosed |
| US-5180652-A | LIGHT- AND HEAT-SENSITIVE COMPOSITION, AND RECORDING MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-4981833-A | Heat sensitive recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130737-B2 | Multifunctional aminoquinoline therapeutic agents | OPRK1, OPRM1, OPRD1 | HRH1 449/4885LMNA 4452/4885SLC5A2 3418/4885 |
| US-20090227652-A1 | INDOLE DERIVATIVES AND METHODS OF USING THE SAME | IDO1, IDO2, INMT | HRH1 1863/4885LMNA 2582/4885SLC5A2 1864/4885 |
| US-20200095204-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | OPRK1, OPRM1, OPRD1 | HRH1 449/4885LMNA 4452/4885SLC5A2 3418/4885 |
| US-10391088-B2 | Analgesic compositions | OPRK1, OPRL1, OPRM1 | HRH1 682/4885LMNA 3291/4885SLC5A2 751/4885 |
| US-20190099412-A1 | ANALGESIC COMPOSITIONS | OPRK1, OPRL1, OPRM1 | HRH1 682/4885LMNA 3291/4885SLC5A2 751/4885 |
| US-20190092731-A1 | MULTIFUNCAIONAL AMINOQUINOLINE THERAPEUTIC AGENT | OPRK1, OPRL1, PNMT | HRH1 455/4885LMNA 4287/4885SLC5A2 3438/4885 |
| US-20170204064-A1 | MULTIFUNCTIONAL AMINOQUINOLINE THERAPEUTIC AGENTS | OPRK1, OPRM1, OPRD1 | HRH1 416/4885LMNA 4487/4885SLC5A2 2834/4885 |
| US-10435371-B2 | Multifunctional aminoquinoline therapeutic agent | OPRK1, OPRM1, OPRD1 | HRH1 434/4885LMNA 4404/4885SLC5A2 3274/4885 |
| US-10112905-B2 | Multifunctional aminoquinoline therapeutic agents | OPRK1, OPRM1, OPRD1 | HRH1 416/4885LMNA 4487/4885SLC5A2 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.