Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | ATR | Q13535 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690402 | 0.88 | GPR119 (0.46) | MCHR1ATRMTORPIK3CAPIK3CG | |
| SCHEMBL13690522 | 0.85 | ATR (0.42) | ATRMTORPIK3CA | |
| SCHEMBL4374631 | 0.83 | ITGB3 (0.40) | MCHR1ATRLTA4H | |
| SCHEMBL4050702 | 0.83 | GPR119 (0.46) | MCHR1ATRATMMTOR | |
| SCHEMBL4056589 | 0.82 | ATR (0.40) | MCHR1ATRMTOR | |
| SCHEMBL4050800 | 0.82 | ALDH1A1 (0.41) | MCHR1ATRSMN1; SMN2 | |
| SCHEMBL4370580 | 0.82 | ATR (0.34) | MCHR1ATRLTA4H | |
| SCHEMBL4060086 | 0.82 | RORC (0.46) | MCHR1ATRMTORPIK3CA | |
| SCHEMBL13690785 | 0.81 | ATR (0.48) | MCHR1ATRMTORPIK3CAPIK3CG | |
| SCHEMBL4048220 | 0.79 | GPR119 (0.44) | MCHR1ATRMTORPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |