SCHEMBL406430

SCHEMBL406430

O=CNCc1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.54
MC5R P33032 2/20 0.51
MAPK1 P28482 1/20 0.51
MC1R Q01726 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 1/20 0.49
ADH1B P00325 1/20 0.48
ADH1C P00326 1/20 0.48
ADH1A P07327 1/20 0.48
ADH7 P40394 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ACP3 P15309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28869987 0.81 CA2 (0.51) CA2MC5RMAPK1MC1RHPGD
SCHEMBL30736517 0.81 MTNR1A (0.57) CA2MAPK1HPGDKMT2AMEN1
SCHEMBL761208 0.81 MTNR1A (0.57) CA2MAPK1HPGDKMT2AMEN1
SCHEMBL6008064 0.81 MC5R (0.70) CA2MC5RMAPK1MC1RHPGD
SCHEMBL8763191 0.81 ADH1B (0.62) CA2KMT2AMEN1ADH1BADH1C
SCHEMBL30595834 0.81 ADH1B (0.62) CA2KMT2AMEN1ADH1BADH1C
SCHEMBL20825026 0.81 CA2 (0.50) CA2MC5RMAPK1MC1RHPGD
SCHEMBL10465513 0.81 CA2 (0.50) CA2MC5RMAPK1MC1RHPGD
SCHEMBL6006432 0.80 KMT2A (0.47) CA2MC5RMAPK1HPGDKMT2A
SCHEMBL5958463 0.79 MEN1 (0.60) CA2HPGDKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US claimed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP claimed
US-20080139456-A1 Macrocyclic Sh2 Domain Binding Inhibitors GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2008-06-12 US claimed
EP-1793843-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS Government of the United States of America, Represented by the Secretary, Department of Health and Human Services (US) 2007-06-13 EP claimed
WO-2006039527-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-13 WO claimed
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SOMALOGIC OPERATING CO., INC. (US) 2024-07-04 US disclosed
WO-2024118776-A1 MATERIALS AND METHODS FOR APTAMER SELECTION THE PENN STATE RESEARCH FOUNDATION (US) 2024-06-06 WO disclosed
CN-118064441-A Methods of producing aptamers with improved dissociation rates 私募蛋白质体运营有限公司 2024-05-24 CN disclosed
EP-4323524-A1 NUCLEIC ACID COMPOUNDS THAT BIND CORONAVIRUS PROTEINS SomaLogic Operating Co., Inc. (US) 2024-02-21 EP disclosed
CN-116334088-A Compositions and methods for detecting microorganisms 私募蛋白质体运营有限公司 2023-06-27 CN disclosed
US-20230193287-A1 Nucleic Acid Compounds for Binding Growth Differentiation Factor 11 SOMALOGIC OPERATING CO., INC. (US) 2023-06-22 US disclosed
US-20230193287-A1 Nucleic Acid Compounds for Binding Growth Differentiation Factor 11 SOMALOGIC OPERATING CO., INC. (US) 2023-06-22 US disclosed
US-5962530-A NEUROPEPTIDE Y ANTAGONIST DR. KARL THOMAE GMBH (DE) 1999-10-05 US disclosed
US-5834460-A FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-11-10 US disclosed
US-5688823-A ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS SANKYO COMPANY, LIMITED (JP) 1997-11-18 US disclosed
US-5578620-A TREATMENT OF DIABETES AND HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1996-11-26 US disclosed
EP-0696586-A1 SERINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-02-14 EP disclosed
EP-0678511-A2 Thiazolidine and oxazolidine derivatives, their preparation and their medical use SANKYO COMPANY LIMITED (JP) 1995-10-25 EP disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX APOL1, UFL1, ACSL3 CA2 3285/4885MC5R 2625/4885MAPK1 2894/4885
US-20230193287-A1 Nucleic Acid Compounds for Binding Growth Differentiation Factor 11 MSTN, S100A11, IGF2BP1 CA2 2173/4885MC5R 3734/4885MAPK1 1729/4885
US-20080139456-A1 Macrocyclic Sh2 Domain Binding Inhibitors ACP1, PPM1D, LASP1 CA2 1144/4885MC5R 4279/4885MAPK1 1106/4885
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SARS1, RNGTT, PABPC1 CA2 1611/4885MC5R 4120/4885MAPK1 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.