Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20730936 | 1.00 | ALDH1A1 (0.53) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL4250939 | 1.00 | ALDH1A1 (0.53) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL11204442 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL4623820 | 0.88 | ALDH1A1 (0.53) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL7793286 | 0.84 | TRPA1 (0.52) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL1617999 | 0.84 | TRPA1 (0.52) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL9763449 | 0.84 | ALDH1A1 (0.50) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL3675071 | 0.83 | ALDH1A1 (0.56) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL1076263 | 0.83 | ALDH1A1 (0.56) | ALDH1A1EPHX1TRPA1TRPM8LMNA | |
| SCHEMBL22130836 | 0.81 | ALDH1A1 (0.51) | ALDH1A1EPHX1TRPA1TRPM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-20230142606-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC AMINO COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-16 | — | — | US | disclosed |
| WO-2020201079-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| US-10689327-B2 | Prodrug amino acid derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-10464884-B2 | Prodrug of amino acid derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190047943-A1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120065152-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2012-03-15 | — | — | US | disclosed |
| US-20090312315-A1 | PAI-1 INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | PAICS, PGLS, SCLY | ALDH1A1 3857/4885EPHX1 4271/4885TRPA1 3480/4885 |
| US-10689327-B2 | Prodrug amino acid derivative | GRIN2A, SLC1A2, SLC1A1 | ALDH1A1 1990/4885EPHX1 2862/4885TRPA1 3709/4885 |
| US-20120065152-A1 | PRODRUGS OF GUANFACINE | UGT1A6, GDA, UGT1A3 | ALDH1A1 270/4885EPHX1 779/4885TRPA1 3637/4885 |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | ALDH1A1 922/4885EPHX1 722/4885TRPA1 108/4885 |
| US-20230142606-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC AMINO COMPOUNDS | DDT, ACHE, DDC | ALDH1A1 1734/4885EPHX1 1307/4885TRPA1 178/4885 |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | ALDH1A1 787/4885EPHX1 1441/4885TRPA1 184/4885 |
| US-10464884-B2 | Prodrug of amino acid derivative | GRIN2A, SLC1A2, SLC1A1 | ALDH1A1 1745/4885EPHX1 3037/4885TRPA1 3943/4885 |
| US-20190047943-A1 | PRODRUG OF AMINO ACID DERIVATIVE | GRIN2A, SLC1A2, SLC1A1 | ALDH1A1 1745/4885EPHX1 3037/4885TRPA1 3943/4885 |
| US-20090312315-A1 | PAI-1 INHIBITOR | SERPINC1, SERPINE1, SERPINH1 | ALDH1A1 1168/4885EPHX1 1249/4885TRPA1 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.