SCHEMBL4079931

SCHEMBL4079931

CCCC(N=C=S)N=C=S

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.52
TRPV1 Q8NER1 2/20 0.52
MIF P14174 2/20 0.34
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483526 0.82 NAAA (0.43) TRPA1TRPV1MIFNAAA
SCHEMBL11507818 0.80 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL6577575 0.80 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL7133116 0.80 NAAA (0.46) TRPA1TRPV1NAAA
SCHEMBL4460900 0.77
SCHEMBL9282879 0.76
SCHEMBL1021266 0.76
SCHEMBL4621487 0.75 TRPA1 (0.35) TRPA1TRPV1NAAA
SCHEMBL4440202 0.75 TRPA1 (0.35) TRPA1TRPV1NAAA
SCHEMBL8100878 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10696778-B1 Methods of making polymers using isosorbide NOVOL, INC. (US) 2020-06-30 US claimed
WO-2024101166-A1 SUBSTRATE PROCESSING METHOD, COMPOSITION FOR FORMING METAL-CONTAINING RESIST, METAL-CONTAINING RESIST, AND SUBSTRATE PROCESSING SYSTEM 東京エレクトロン株式会社 2024-05-16 WO disclosed
US-11780950-B1 Methods of making polymers using isosorbide Bhatia, Monica (US) 2023-10-10 US disclosed
EP-3743453-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS Novol, Inc. (US) 2020-12-02 EP disclosed
US-10696778-B1 Methods of making polymers using isosorbide NOVOL, INC. (US) 2020-06-30 US disclosed
WO-2019147848-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. (US) 2019-08-01 WO disclosed
US-8445581-B2 Biocompatible polymer compositions POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2013-05-21 US disclosed
US-20090324675-A1 BIOOCOMPATIBLE POLYMER COMPOSITIONS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2009-12-31 US disclosed
EP-2049591-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS Polynovo Biomaterials Pty Limited (AU) 2009-04-22 EP disclosed
WO-2009038937-A1 TINTED ARTICLE HAVING A HIGH REFRACTIVE INDEX PPG INDUSTRIES OHIO, INC. (US) 2009-03-26 WO disclosed
EP-2004717-A2 POLY(UREAURETHANE)S, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG Industries Ohio, Inc. (US) 2008-12-24 EP disclosed
WO-2008014561-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS POLYNOVO BIOMATERIALS PTY LTD (AU) 2008-02-07 WO disclosed
WO-2007139586-A2 POLY(UREAURETHANE)S, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-12-06 WO disclosed
WO-2007073474-A1 IMPACT RESISTANT POLYURETHANE AND POLY(UREAURETHANE) ARTICLES AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-28 WO disclosed
WO-2007070627-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-21 WO disclosed
EP-1120435-B1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LTD (JP) 2004-05-06 EP disclosed
US-6562936-B1 Resin excellent in hydrolysis and heat stability such as a reduction in molecular weight at the time of molding and color retention and moldability such as releasability and transferability, rarely experiences residence deterioration TEIJIN LIMITED (JP) 2003-05-13 US disclosed
US-6509435-B1 Heat resistance, stability; moldings TEIJIN LIMITED (JP) 2003-01-21 US disclosed
EP-1191049-A1 POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-03-27 EP disclosed
EP-1120435-A1 APPARATUS AND METHOD FOR PRODUCING RESIN TEIJIN LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780950-B1 Methods of making polymers using isosorbide PUF60, MACF1, PPIE TRPA1 887/4885TRPV1 2491/4885MIF 713/4885
US-20090324675-A1 BIOOCOMPATIBLE POLYMER COMPOSITIONS HPGDS, PGF, PIGS TRPA1 1391/4885TRPV1 383/4885MIF 273/4885
US-10696778-B1 Methods of making polymers using isosorbide PUF60, MACF1, PPIE TRPA1 1297/4885TRPV1 2456/4885MIF 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.