SCHEMBL409318

SCHEMBL409318

CC(=O)CCc1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
FFAR1 O14842 1/20 0.55
SLC5A1 P13866 1/20 0.51
SLC5A2 P31639 1/20 0.51
HPGD P15428 1/20 0.51
PLAAT3 P53816 1/20 0.47
PLAAT5 Q96KN8 1/20 0.47
PLAAT2 Q9NWW9 1/20 0.47
PLAAT4 Q9UL19 1/20 0.47
MAOA P21397 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
SLC6A2 P23975 1/20 0.47
RAB9A P51151 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134877 0.91 S1PR1 (0.58) ALDH1A1FFAR1SLC5A1SLC5A2HPGD
Benzylacetone SCHEMBL27625519 0.90 ALDH1A1 (0.81) ALDH1A1FFAR1PLAAT3PLAAT5PLAAT2
SCHEMBL10912165 0.89 ALDH1A1 (0.77) ALDH1A1FFAR1MAOAKDM4ENPC1
SCHEMBL11543795 0.88 LMNA (0.53) ALDH1A1FFAR1SLC5A1SLC5A2HPGD
SCHEMBL11536859 0.86 NAAA (0.50) ALDH1A1FFAR1HPGDLMNAMAPT
SCHEMBL11243506 0.85 FFAR1 (0.57) ALDH1A1FFAR1KDM4ELMNAMAPT
SCHEMBL9627732 0.85 MAOB (0.68) FFAR1MAOAMAOB
SCHEMBL11638377 0.84 FAAH (0.50) ALDH1A1FFAR1HPGDLMNAMAPT
SCHEMBL16638504 0.83 ALDH1A1 (0.63) ALDH1A1FFAR1MAOAKDM4ENPC1
SCHEMBL9253136 0.82 TAAR1 (0.50) FFAR1SLC5A1SLC5A2HPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808411-B Notebook computer shell and injection molding process thereof 安徽英力电子科技股份有限公司 2022-04-19 CN claimed
CN-111808411-A Notebook computer shell and injection molding process thereof 合肥佐佑信息技术有限公司 2020-10-23 CN claimed
CN-105384707-B A kind of preparation method of α amino acetophenones light trigger 山东久日化学科技有限公司 2018-04-17 CN claimed
US-20260115188-A1 METHODS OF TREATING CENTERAL NERVOUS SYSTEM DISORDERS COMPRISING ADMINISTERING DEUTERATED LUMATEPERONE AND A NITRIC OXIDE DONOR INTRA-CELLULAR THERAPIES, INC. (US) 2026-04-30 US disclosed
US-20260053748-A1 NOVEL METHODS INTRA CELLULAR THERAPIES INC (US) 2026-02-26 US disclosed
EP-3768271-B1 ORGANIC COMPOUNDS INTRA CELLULAR THERAPIES INC (US) 2026-02-18 EP disclosed
US-12533355-B2 Methods of treatment comprising administering lumateperone mono-tosylate capsules INTRA-CELLULAR THERAPIES, INC. (US) 2026-01-27 US disclosed
US-12521410-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2026-01-13 US disclosed
US-12496300-B2 Methods of treating acute depression and anxiety INTRA-CELLULAR THERAPIES, INC. (US) 2025-12-16 US disclosed
US-12478623-B2 Methods of treating central nervous system disorders comprising administering lumateperone and a nitric oxide donor INTRA-CELLULAR THERAPIES, INC. (US) 2025-11-25 US disclosed
US-20250352469-A1 NOVEL COMPOSITIONS, DEVICES, AND METHODS INTRA CELLULAR THERAPIES INC (US) 2025-11-20 US disclosed
US-20070123563-A1 Selective androgen receptor modulators and method of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2007-05-31 US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
WO-2006089038-A2 INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-08-24 WO disclosed
WO-2005009392-A2 DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION BRISTOL-MYERS SQUIBB COMPANY (US) 2005-02-03 WO disclosed
CN-1209125-A Piperazine derivatives as tachykinin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1999-02-24 CN disclosed
EP-0306440-A2 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents SCHERING AKTIENGESELLSCHAFT (DE) 1989-03-08 EP disclosed
US-4160036-A ADRENERGIC STIMULANTS ALLEN & HANBURYS LIMITED (GB) 1979-07-03 US disclosed
US-4140713-A Phenylethanolamine therapeutic agents ALLEN & HANBURYS LIMITED (GB) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533355-B2 Methods of treatment comprising administering lumateperone mono-tosylate capsules HTR2C, SLC6A4, SLC6A2 ALDH1A1 1128/4885FFAR1 336/4885SLC5A1 77/4885
US-20250352469-A1 NOVEL COMPOSITIONS, DEVICES, AND METHODS LIPA, DHCR7, HSD17B7 ALDH1A1 2752/4885FFAR1 284/4885SLC5A1 294/4885
US-20070123563-A1 Selective androgen receptor modulators and method of use thereof AR, SHBG, ESRRA ALDH1A1 2077/4885FFAR1 183/4885SLC5A1 999/4885
US-20260053748-A1 NOVEL METHODS HTR1D, HTR2C, HTR1A ALDH1A1 529/4885FFAR1 490/4885SLC5A1 850/4885
US-12496300-B2 Methods of treating acute depression and anxiety HTR2A, HTR1A, HTR3B ALDH1A1 1650/4885FFAR1 631/4885SLC5A1 3320/4885
US-20260115188-A1 METHODS OF TREATING CENTERAL NERVOUS SYSTEM DISORDERS COMPRISING ADMINISTERING DEUTERATED LUMATEPERONE AND A NITRIC OXIDE DONOR HTR2C, DRD2, HTR2A ALDH1A1 669/4885FFAR1 81/4885SLC5A1 756/4885
US-12478623-B2 Methods of treating central nervous system disorders comprising administering lumateperone and a nitric oxide donor HTR2A, HTR2C, HTR5A ALDH1A1 436/4885FFAR1 152/4885SLC5A1 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.